Preparation, characterization, and evaluation of cisplatin-loaded polybutylcyanoacrylate nanoparticles with improved in vitro and in vivo anticancer activities

M Ghaferi, S Amari, B Vivek Mohrir, A Raza… - Pharmaceuticals, 2020 - mdpi.com
This study aimed to evaluate the therapeutic efficacy of the cisplatin encapsulated into
polybutylcyanoacrylate (PBCA) nanoparticles for the treatment of kidney cancer. The …

Enhancing anti-cancer efficacy of carboplatin by PEGylated poly (butyl cyanoacrylate) nano-particles

M Hassanzadeganroudsari, A Heydarinasab… - Journal of Drug Delivery …, 2019 - Elsevier
Nano-drug delivery holds great potential to enhance the efficacy of carboplatin. This study
focused on cytotoxicity, in vitro drug release and characterization of poly (butyl …

Cisplatin-loaded polybutylcyanoacrylate nanoparticles with improved properties as an anticancer agent

SE Alavi, S Muflih Al Harthi… - International Journal of …, 2019 - mdpi.com
This study aims to improve the cytotoxicity and potency of cisplatin-loaded
polybutylcyanoacrylate (PBCA) nanoparticles (NPs) for the treatment of lung cancer through …

Investigating the properties and cytotoxicity of cisplatin-loaded nano-polybutylcyanoacrylate on breast cancer cells

A Gorgzadeh, A Hheidari, P Ghanbarikondori… - Asian Pacific Journal of …, 2023 - waocp.com
Background: This study aimed to develop a novel drug formulation using
polybutylcyanoacrylate (PBCA) nanoparticles to deliver cisplatin, a commonly used …

Efficacy of Cisplatin-loaded poly butyl cyanoacrylate nanoparticles on the ovarian cancer: an in vitro study

SK Bagherpour Doun, SE Alavi… - Tumor Biology, 2014 - Springer
One of the main challenges of treatment of ovarian cancer is initial response to treatment
and then acquisition of resistance to Cisplatin. Nanotechnology-based approaches are …

Efficacy of Cisplatin-loaded polybutyl cyanoacrylate nanoparticles on the glioblastoma

H Ebrahimi Shahmabadi, F Movahedi… - Tumor Biology, 2014 - Springer
Glioblastoma is known as one of the most aggressive human cancers. To gain access of the
brain, therapeutic agents must overcome blood–brain barrier (BBB). In this study, Cisplatin …

[HTML][HTML] Toxicity of cisplatin-loaded poly butyl cyanoacrylate nanoparticles in a brain cancer cell line: Anionic polymerization results

N Mohamadi, SM Kazemi… - Asian Pacific Journal …, 2017 - ncbi.nlm.nih.gov
Cancer is one of the most important issues in modern medicine and the most common cause
of death after cardiovascular diseases in many countries. Brain cancer is one of the most …

Synthesis of high loading and encapsulation efficient paclitaxel-loaded poly (n-butyl cyanoacrylate) nanoparticles via miniemulsion

CY Huang, CM Chen, YD Lee - International journal of pharmaceutics, 2007 - Elsevier
The manufacture of stable paclitaxel-loaded poly (n-butyl cyanoacrylate)(PBCA)
nanoparticles containing high loading and encapsulation efficiency simultaneously were …

Hyaluronic acid coated poly (butyl cyanoacrylate) nanoparticles as anticancer drug carriers

M He, Z Zhao, L Yin, C Tang, C Yin - International journal of pharmaceutics, 2009 - Elsevier
The hyaluronic acid (HA) coated poly (butyl cyanoacrylate)(PBCA) nanoparticles were
synthesized through radical polymerization of butyl cyanoarylate (BCA) initiated by cerium …

Poly (ɛ-caprolactone) nanoparticles of carboplatin: Preparation, characterization and in vitro cytotoxicity evaluation in U-87 MG cell lines

V Karanam, G Marslin, B Krishnamoorthy… - Colloids and Surfaces B …, 2015 - Elsevier
Carboplatin is a platinum based drug used in the treatment of several malignancies. Due to
poor cellular uptake, generally, a larger dose of drug is administered to achieve therapeutic …