A comprehensive study of laboratory-based micro-CT for 3D virtual histology of human FFPE tissue blocks

K Tajbakhsh, A Neels, E Fadeeva, JC Larsson… - IEEE …, 2024 - ieeexplore.ieee.org
Advances in laboratory-based X-ray computed tomography (CT) have enabled X-ray 3D
virtual histology. This method shows a great potential as a complementary technique to …

A comprehensive study of micro-CT for 3D virtual histology of FFPE tissue blocks

K Tajbakhsh, A Neels, E Fadeeva, JC Larsson… - Authorea …, 2024 - techrxiv.org
Advances in X-ray computed tomography (CT) has enabled soft-tissue X-ray imaging with
improved contrast and resolution. As a result, non-destructive X-ray 3D virtual histology is …

[HTML][HTML] A high-throughput 3D X-ray histology facility for biomedical research and preclinical applications

OL Katsamenis, PJ Basford, SK Robinson… - Wellcome Open …, 2023 - ncbi.nlm.nih.gov
Background The University of Southampton, in collaboration with the University Hospital
Southampton (UHS) NHS Foundation Trust and industrial partners, has been at the forefront …

X-ray based virtual histology allows guided sectioning of heavy ion stained murine lungs for histological analysis

J Albers, MA Markus, F Alves, C Dullin - Scientific reports, 2018 - nature.com
Examination of histological or immunohistochemically stained 2D sections of embedded
tissue is one of the most frequently used tools in biomedical research and clinical routine …

Nucleus-specific X-ray stain for 3D virtual histology

M Müller, MA Kimm, S Ferstl, S Allner, K Achterhold… - Scientific reports, 2018 - nature.com
Histological investigations are indispensable with regards to the identification of structural
tissue details but are limited to two-dimensional images, which are often visualized in one …

X-ray-based 3D virtual histology—Adding the next dimension to histological analysis

J Albers, S Pacilé, MA Markus, M Wiart… - Molecular Imaging and …, 2018 - Springer
Histology and immunohistochemistry of thin tissue sections have been the standard
diagnostic procedure in many diseases for decades. This method is highly specific for …

FleXCT: a flexible X-ray CT scanner with 10 degrees of freedom

BD Samber, J Renders, T Elberfeld, Y Maris… - Optics …, 2021 - opg.optica.org
Laboratory based X-ray micro-CT is a non-destructive testing method that enables three
dimensional visualization and analysis of the internal and external morphology of samples …

X-ray phase contrast 3D virtual histology: evaluation of lung alterations after microbeam irradiation

M Romano, MD Wright, L Jacques, A Miettinen… - International Journal of …, 2022 - Elsevier
Purpose This study provides the first experimental application of multiscale 3-dimensional
(3D) x-ray phase contrast imaging computed tomography (XPCI-CT) virtual histology for the …

Preparation of large biological samples for high-resolution, hierarchical, multi-modal imaging

J Brunet, CL Walsh, WL Wagner, A Bellier, C Werlein… - bioRxiv, 2022 - biorxiv.org
Imaging the different scales of biological tissue is essential for understanding healthy organ
behavior and pathophysiological changes. X-ray micro-tomography using both laboratory …

[HTML][HTML] From micro-to nano-and time-resolved x-ray computed tomography: Bio-based applications, synchrotron capabilities, and data-driven processing

PIC Claro, EPBS Borges, GR Schleder… - Applied Physics …, 2023 - pubs.aip.org
X-ray computed microtomography (μCT) is an innovative and nondestructive versatile
technique that has been used extensively to investigate bio-based systems in multiple …