RecT affects prophage lifestyle and host core cellular processes in Pseudomonas aeruginosa

X Long, H Zhang, X Wang, D Mao… - Applied and …, 2022 - Am Soc Microbiol
Pseudomonas aeruginosa is a notorious pathogen that causes various nosocomial
infections. Several prophage genes located on the chromosomes of P. aeruginosa have …

Emergence of Small Colony Variants (SCVs) is an adaptive strategy used by Pseudomonas aeruginosa to palliate O2 limitations

A Besse, MC Groleau, E Déziel - bioRxiv, 2022 - biorxiv.org
The ability to generate a subpopulation of Small Colony Variants (SCVs) is a conserved
feature of Pseudomonas aeruginosa and could represent a key adaptive strategy to colonize …

Cystic Fibrosis-Niche Adaptation of Pseudomonas aeruginosa Reduces Virulence in Multiple Infection Hosts

NI Lorè, C Cigana, I De Fino, C Riva, M Juhas… - PloS one, 2012 - journals.plos.org
The opportunistic pathogen Pseudomonas aeruginosa is able to thrive in diverse ecological
niches and to cause serious human infection. P. aeruginosa environmental strains are …

Bacterial community structure and mucin drive Pseudomonas aeruginosa diversification and pathoadaptation

HK Johansen, J Pitchford, VP Friman, M Bottery - 2023 - researchsquare.com
While several environmental factors contribute to the evolutionary diversification of the
pathogenic bacterium Pseudomonas aeruginosa during cystic fibrosis lung infections …

[HTML][HTML] Advances in understanding Pseudomonas

B Tümmler, L Wiehlmann, J Klockgether… - F1000prime …, 2014 - ncbi.nlm.nih.gov
Pseudomonas aeruginosa, the type species of pseudomonads, is an opportunistic pathogen
that colonizes a wide range of niches. Current genome sequencing projects are producing …

Can we manipulate the evolutionary biology of pathogens for clinical benefit?

C Winstanley, MA Brockhurst - American Journal of Respiratory Cell …, 2018 - atsjournals.org
The analysis of readily available sputum samples from long-term chronic Pseudomonas
aeruginosa infections in the cystic fibrosis (CF) lung has provided unique insights into the …

Characterization and interstrain transfer of prophage pp3 of Pseudomonas aeruginosa

G Li, S Lu, M Shen, S Le, W Shen, Y Tan, J Wang… - Plos one, 2017 - journals.plos.org
Prophages are major contributors to horizontal gene transfer and drive the evolution and
diversification of bacteria. Here, we describe the characterization of a prophage element …

Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung

A Kordes, M Preusse, SD Willger, P Braubach… - Nature …, 2019 - nature.com
Previous studies have demonstrated substantial genetic diversification of Pseudomonas
aeruginosa across sub-compartments in cystic fibrosis (CF) lungs. Here, we isolate P …

Evolutionary Genomics of Niche-Specific Adaptation to the Cystic Fibrosis Lung in Pseudomonas aeruginosa

JR Dettman, R Kassen - Molecular biology and evolution, 2021 - academic.oup.com
The comparative genomics of the transition of the opportunistic pathogen Pseudomonas
aeruginosa from a free-living environmental strain to one that causes chronic infection in the …

Prophage identification and molecular analysis in the genomes of Pseudomonas aeruginosa strains isolated from critical care patients

M González de Aledo, L Blasco, M Lopez… - Msphere, 2023 - Am Soc Microbiol
Prophages are bacteriophages integrated into the bacterial host's chromosome. This
research aims to analyze and characterize the existing prophages within a collection of 53 …