Carcinogen exposure among Canadian tobacco users: changes in NNK exposure from 2007–2009 through 2012–2013

CD Czoli, D Hammond - Cancer Epidemiology, Biomarkers & Prevention, 2018 - AACR
Abstract Background: Tobacco-specific nitrosamines (TSNAs) are a class of carcinogens
found in tobacco products, whose levels can vary considerably depending on tobacco …

TSNA exposure: levels of NNAL among Canadian tobacco users

CD Czoli, D Hammond - Nicotine & Tobacco Research, 2015 - academic.oup.com
Introduction: Tobacco smoke contains more than 7,000 chemicals, including known
carcinogens, such as tobacco-specific nitrosamines (TSNAs). TSNA levels in cigarettes vary …

Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers

DL Ashley, RJ O'Connor, JT Bernert, CH Watson… - … , biomarkers & prevention, 2010 - AACR
Background: Smokers are exposed to significant doses of carcinogens, including tobacco-
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …

Assessing exposure to tobacco-specific carcinogen NNK using its urinary metabolite NNAL measured in US population: 2011–2012

B Wei, BC Blount, B Xia, L Wang - Journal of exposure science & …, 2016 - nature.com
Carcinogenic tobacco-specific nitrosamines (TSNAs) such as 4-(methylnitrosamino)-1-(3-
pyridyl)-1-butanone (NNK) are found only in tobacco and derived products. Food and Drug …

Trends over time in tobacco-specific nitrosamines (TSNAs) in whole tobacco and smoke emissions from cigarettes sold in Canada

CD Czoli, D Hammond - Nicotine and Tobacco Research, 2018 - academic.oup.com
Abstract Introduction Tobacco-specific nitrosamines (TSNAs) are potent carcinogens. Levels
of TSNAs can be modified through manufacturing practices. In the 2000s, TSNA levels in …

Tobacco-specific nitrosamines (NNAL, NNN, NAT, and NAB) exposures in the US Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013–2014)

B Xia, BC Blount, T Guillot, C Brosius… - Nicotine and …, 2021 - academic.oup.com
Introduction The tobacco-specific nitrosamines (TSNAs) are an important group of
carcinogens found in tobacco and tobacco smoke. To describe and characterize the levels …

Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in smokers in the United States: NHANES 2007–2008

Y Xia, JT Bernert, RB Jain, DL Ashley, JL Pirkle - Biomarkers, 2011 - Taylor & Francis
The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a
metabolite of the tobacco-specific nitrosamine (TSNA) 4-(methylnitrosamino)-1-(3-pyridyl)-1 …

Determination of carcinogenic tobacco-specific nitrosamines in mainstream smoke from US-brand and non-US-brand cigarettes from 14 countries

W Wu, L Zhang, RB Jain, DL Ashley… - Nicotine & tobacco …, 2005 - academic.oup.com
Tobacco-specific nitrosamines (TSNAs) comprise one of the major classes of carcinogenic
compounds in mainstream cigarette smoke. As part of collaborative efforts between the …

Tobacco-specific nitrosamines in tobacco from US brand and non-US brand cigarettes

DL Ashley, MD Beeson, DR Johnson… - Nicotine & tobacco …, 2003 - academic.oup.com
Tobacco-specific nitrosamines (TSNAs) are one of the major classes of carcinogens found in
tobacco products. As part of collaborative efforts to reduce tobacco use and resulting …

Quantitation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine by LC tandem mass spectrometry

Y Xia, JT Bernert - Epidemiology, 2008 - journals.lww.com
Background: The tobacco-specific nitrosamine (TSNA) 4-(Methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK) is a powerful pulmonary carcinogen in rodents, and it is believed to be a …