Environmental experiences play a critical role in shaping the structure and function of the
brain. Its plasticity in response to different external stimuli has been the focus of research …

There is robust evidence that a host of environmental features influence neurobiological
factors that contribute to risk for mental health challenges. This compelling body of evidence …

The developing human brain is shaped by environmental exposures—for better or worse.
Many exposures relevant to mental health are genuinely social in nature or believed to have …

It is understood that adversity during development has the power to alter behavioral
trajectories, and the role of the epigenome in that relationship is currently under intense …

Environmental experiences play a powerful role in shaping mental health across the
lifecourse. Exposure to trauma, socioeconomic disadvantage, and other forms of chronic …

Environmental adversities constitute potent risk factors for psychiatric disorders. Evidence
suggests the brain adapts to adversity, possibly in an adversity-type and region-specific …

Given the high prevalence and burden of mental disorders, fostering the understanding of
protective factors is an urgent issue for translational medicine in psychiatry. The concept of …

Early adverse environmental exposures during brain development are widespread risk
factors for the onset of severe mental disorders and strong and consistent predictors of …

Background Adversity experiences (AEs) are major risk factors for psychiatric illness, and
ample evidence suggests that adversity‐related changes in brain structure enhance this …

Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …