The environment influences brain and mental health, both detrimentally and beneficially.
Existing research has emphasised the individual psychosocial 'microenvironment'. Less …

Background Childhood maltreatment has been associated with significant impairment in
social, emotional and behavioural functioning later in life. Nevertheless, some individuals …

Childhood experiences play a profound role in conferring risk and resilience for brain and
behavioral development. However, how different facets of the environment shape …

Early-life adversities (ELA) are associated with subsequent pervasive alterations across a
wide range of neurobiological systems and psychosocial factors that contribute to …

Abstract The review by Koss & Gunna provides a scholarly overview of the role of the
hypothalamic‐pituitary‐adrenal (HPA) axis in mediating the association between childhood …

Exposure to early adversity (EA) is associated with long-lasting dysregulations in cognitive
processes sustained by brain regions that are sensitive to stress hormones: the …

Childhood adversity (CA) as a significant stressor has consistently been associated with the
development of mental disorders. The interaction between CA and genetic variants has …

Childhood adversity (CA) has been associated with long-term structural brain alterations
and an increased risk for psychiatric disorders. Evidence is emerging that subtypes of CA …

Comprehensive clinical studies show that adverse conditions in early life can severely
impact the developing brain and increase vulnerability to mood disorders later in life. During …

Early life adversity is associated with differences in brain function and an elevated risk for
poor mental health. Using data from children aged 10 (N= 5,798) from the Adolescent Brain …