A combined proteomics and metabolomics approach was utilised to advance the
identification and characterisation of secondary metabolites in Aspergillus fumigatus. Here …

Background Aspergillus fumigatus produces a number of secondary metabolites, one of
which, gliotoxin, has been shown to exhibit anti-fungal activity. Thus, A. fumigatus must be …

Gliotoxin is an epipolythiodioxopiperazine (ETP) class toxin, contains a disulfide bridge that
mediates its toxic effects via redox cycling and is produced by the opportunistic fungal …

Gliotoxin, a major product of the gli non-ribosomal peptide synthetase gene cluster, is
strongly associated with virulence of the opportunistic human pathogen Aspergillus …

The opportunistic pathogenic mold Aspergillus fumigatus is an increasing cause of morbidity
and mortality in immunocompromized and in part immunocompetent patients. A. fumigatus …

Aspergillus fumigatus is a saprophytic fungus that causes a range of diseases in humans
including invasive aspergillosis. All forms of disease begin with the inhalation of conidia …

In this review, we present a comprehensive overview of the current status of genomics,
transcriptomics, proteomics, metabolomics, and metabolic modeling in Aspergillus species …

Incidence rates of infections caused by environmental opportunistic fungi have risen over
recent decades. Aspergillus species have emerged as serious threat for the …

Aspergillus species are the major cause of health concern worldwide in
immunocompromised individuals. Opportunistic Aspergilli cause invasive to allergic …

NADPH-oxidase mediated production of Reactive Oxygen Species (ROS) by alveolar
macrophages and neutrophils is a critical mechanism for immune defence against …