Chalcones in their various guises have been considered either valid and critically important
lead compounds in the development of novel anticancer agents or as pan assay …

The need for innovative anticancer treatments with high effectiveness and low toxicity is
urgent due to the development of malignancies that are resistant to chemotherapeutic …

A series of 59 chalcones was prepared and evaluated for the antimitotic effect against K562
leukemia cells. The most active chalcones were evaluated for their antiproliferative activity …

Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …

Chalcones are naturally occurring compounds exhibiting broad spectrum biological
activities including anticancer activity through multiple mechanisms. Literature on anticancer …

There is an emerging paradigm shift in oncology that seeks to emphasize molecularly
targeted approaches for cancer prevention and therapy. Chalcones (1, 3-diphenyl-2-propen …

Cancer has eventually stepped into the molecular insights focussing on the development of
new generation of anticancer drugs especially of natural origin and its analogues with less …

One part of chemical space that is endowed with interesting biological properties is the area
of the chalcones. With this review, we provide a comprehensive overview of the numerous in …

Natural or synthetic chalcones with different substituents have revealed a variety of
biological activities that may benefit human health. The underlying mechanisms of action …

Chalcones (1, 3-diaryl-2-propen-1-ones) are precursors for flavonoids and isoflavonoids,
which are common simple chemical scaffolds found in many naturally occurring compounds …