[HTML][HTML] Comparative analysis of the safety and tolerability of eslicarbazepine acetate in older (≥ 60 years) and younger (18–59 years) adults

E Andermann, W Rosenfeld, P Penovich, J Rogin… - Epilepsy Research, 2021 - Elsevier
Objective To investigate the safety and tolerability of eslicarbazepine acetate (ESL), a once-
daily oral anti-seizure drug (ASD), in older and younger adult patient populations. Methods …

Safety of eslicarbazepine acetate in elderly versus non-elderly patients with focal seizures: from pooled data of clinical studies to 8 years of post-marketing experience

LM Magalhães, R Costa, M Vieira, J Moreira, H Gama… - Drug Safety, 2021 - Springer
Introduction The prevalence of epilepsy increases in elderly patients aged> 65 years, and
treatment is challenging because clinical data are limited. Objective Our objective was to …

Effectiveness and safety/tolerability of eslicarbazepine acetate in epilepsy patients aged≥ 60 versus< 60 years: a subanalysis from the Euro-Esli Study

C Lawthom, P Bermejo, D Campos, R McMurray… - Neurology and …, 2019 - Springer
Introduction Clinical practice studies help guide antiepileptic drug (AED) therapy in patient
groups routinely excluded from clinical trials, such as the elderly. The Euro-Esli study …

[HTML][HTML] Efficacy and safety of eslicarbazepine-acetate in elderly patients with focal epilepsy: case series

A Gómez-Ibáñez, JM Serratosa, E Guillamón, M Garcés… - Seizure, 2017 - Elsevier
Purpose Eslicarbazepine-acetate (ESL) is a third generation antiepileptic drug licensed as
adjunctive therapy in adults with focal seizures. Efficacy and safety of ESL have been …

[HTML][HTML] Clinical experience with eslicarbazepine acetate in adults with sub-analysis of elderly

MK Nielsen, V Petrenaite, NB Andersen - Seizure, 2017 - Elsevier
Purpose Eslicarbazepine acetate (ESL) is indicated for treatment of focal epilepsy. Our aim
was to evaluate the effect and tolerability of ESL in elderly and younger adults. The primary …

Safety, tolerability and efficacy of eslicarbazepine acetate as adjunctive therapy in patients aged≥ 65 years with focal seizures

R Costa, B Steinhoff, H Gama, F Ikedo, JF Rocha… - Drugs & Aging, 2018 - Springer
Background The incidence of epilepsy is high within the first few years of life, stabilizes over
the second through fifth decades, and then rises again. Treatment of elderly patients with …

Clinical outcomes of eslicarbazepine acetate monotherapy for focal‐onset seizures: A multicenter audit

BG Giráldez, I Garamendi‐Ruiz, J Zurita… - Acta Neurologica …, 2019 - Wiley Online Library
Objective To assess the effectiveness and tolerability of eslicarbazepine acetate (ESL)
monotherapy in routine clinical practice for the treatment of focal‐onset seizures. Methods …

Long-term safety and efficacy of eslicarbazepine acetate as adjunctive therapy in the treatment of partial-onset seizures in adults with epilepsy: results of a 1-year …

A Hufnagel, E Ben-Menachem, AA Gabbai, A Falcão… - Epilepsy Research, 2013 - Elsevier
OBJECTIVE: To evaluate the long-term safety, tolerability and efficacy of once-daily
eslicarbazepine acetate (ESL) as adjunctive therapy in adults with partial-onset seizures …

Eslicarbazepine acetate: a review of its use as adjunctive therapy in refractory partial-onset seizures

GM Keating - CNS drugs, 2014 - Springer
Abstract Eslicarbazepine acetate (Aptiom®, Zebinix®) is approved for the adjunctive
treatment of partial-onset seizures in adults aged≥ 18 years. Adjunctive therapy with oral …

Safety profile of eslicarbazepine acetate as add-on therapy in adults with refractory focal-onset seizures: from clinical studies to 6 years of post-marketing experience

H Gama, M Vieira, R Costa, J Graça, LM Magalhães… - Drug Safety, 2017 - Springer
Introduction Eslicarbazepine acetate was first approved in the European Union in 2009 as
adjunctive therapy in adults with partial-onset seizures with or without secondary …