Elevated levels of alkaline phosphatase (ALP) in the tumor microenvironment (TME) are a
hallmark of cancer progression and thus inhibition of ALP could serve as an effective …

Alkaline Phosphatase (ALP) is known as one of the most crucial members of phosphatase
family and encompasses the enormous ability to hydrolyze the phosphate group in various …

Objective: In this study, three-dimensional (3D) structures of lung cancer cell line proteins
(cellular tumor antigen [p53], caspase 3, and mucosal addressin cell adhesion molecule 1) …

Abstract Protein phosphatase 1 (PP1) is a critical regulator of several processes, such as
muscle contraction, neuronal signaling, glycogen synthesis, and cell proliferation …

A novel potentially biologically active oxazaphosphinane derivatives was synthesized by
facile synthetic approaches from the combination of hydroxyaniline, aldehyde, and …

The liver function test is an imperative element in chemotherapy management due to the
idiosyncratic reaction of chemotherapy drugs. This study primly aimed to replace the toxic …

Cancer is a complicated malignancy controlled by numerous intrinsic and extrinsic
pathways. There has been a significant increase in interest in recent years in the elucidation …

In silico docking studies serve as a swift and efficient means to sift through a vast array of
natural and synthetic small molecules, aiding in the identification of potential inhibitors for …

Natural products have emerged as major leads for the discovery and development of new
anti-cancer drugs. The plant-derived anti-cancer drugs account for approximately 60% and …

Etoposide is a cancer-targeting drug but an overdose of etoposide leads to
immunosuppression in patients. Therefore, the development of a new strategy to enhance its …