Oxidative stress-mediated damage to functional macromolecules followed by their
accumulation has been reported as a major factor behind aging and related consequences …

Aging researches have experienced an unprecedented advance over recent years. The
comprehension of process leading to age-associated alterations is at moment of the highest …

Aging is a gradual, complex process in which cells, tissues, organs, and the whole organism
itself deteriorate in a progressive and irreversible manner that, in the majority of cases …

Basal levels of oxidants are indispensible for redox signaling to produce adaptive cellular
responses such as vitagenes linked to cell survival; however, at higher levels, they are …

There is still ongoing controversy about the oxidative stress theory of aging, particularly in
mammals, after a significant number of studies have been conducted to test this theory …

Oxidative damage accumulation in macromolecules has been considered as causative of
cellular damage and pathology. Considering early observations of Gershman that oxygen …

The relationship between oxidants and organismal aging was first articulated through the
free radical theory of aging. One of the major predictions of the free radical theory of aging is …

Oxidative stress has emerged as a critical player in the pathogenesis and pathophysiology
of many diseases in experimental animal models and humans. The oxidative stress theory of …

This multi-chapter book is dedicated to present age-related alterations in redox signaling
networks and their diagnostic biomarkers in aging cell. Establishing sensitive and specific …

This multi-chapter book is dedicated to present age-related alterations in redox signaling
networks and their diagnostic biomarkers in aging cell. Establishing sensitive and specific …