Evaluation of genetic polymorphisms associated with the metabolic effects of aripiprazole and olanzapine
D Koller - 2020 - digital.csic.es
Aripiprazole and olanzapine are atypical antipsychotics. Both drugs can induce metabolic
and cardiovascular changes and adverse drug reactions. Pupillography is a non-invasive …
and cardiovascular changes and adverse drug reactions. Pupillography is a non-invasive …
The effects of Aripiprazole and olanzapine on pupillary light reflex and its relationship with Pharmacogenetics in a randomized Multiple‐Dose trial
Aims Pupillography is a noninvasive and cost‐effective method to determine autonomic
nerve activity. Genetic variants in cytochrome P450 (CYP), dopamine receptor (DRD2 …
nerve activity. Genetic variants in cytochrome P450 (CYP), dopamine receptor (DRD2 …
Effects of aripiprazole on pupillometric parameters related to pharmacokinetics and pharmacogenetics after single oral administration to healthy subjects
D Koller, C Belmonte, R Lubomirov… - Journal of …, 2018 - journals.sagepub.com
Background: Pupillometry is used for the detection of autonomic dysfunction related to
numerous diseases and drug administration. Genetic variants in cytochrome P450 …
numerous diseases and drug administration. Genetic variants in cytochrome P450 …
Metabolic effects of aripiprazole and olanzapine multiple-dose treatment in a randomised crossover clinical trial in healthy volunteers: association with …
D Koller, S Almenara, G Mejía, M Saiz-Rodríguez… - Advances in …, 2021 - Springer
Introduction Aripiprazole and olanzapine are atypical antipsychotics. Both drugs can induce
metabolic changes; however, the metabolic side effects produced by aripiprazole are more …
metabolic changes; however, the metabolic side effects produced by aripiprazole are more …
Genetic polymorphisms associated with the pharmacokinetics, pharmacodynamics and adverse effects of olanzapine, aripiprazole and risperidone
P Soria-Chacartegui, G Villapalos-García… - Frontiers in …, 2021 - frontiersin.org
Olanzapine, aripiprazole and risperidone are atypical antipsychotics or neuroleptics widely
used for schizophrenia treatment. They induce various adverse drug reactions depending …
used for schizophrenia treatment. They induce various adverse drug reactions depending …
Metabolic effects of aripiprazole and olanzapine multiple-dose treatment in healthy volunteers. Association with pharmacogenetics
D Koller, S Almenara, G Mejía, M Saiz-Rodríguez… - bioRxiv, 2020 - biorxiv.org
Background Aripiprazole and olanzapine are atypical antipsychotics. Both drugs can induce
metabolic changes, however, the metabolic side effects produced by aripiprazole are more …
metabolic changes, however, the metabolic side effects produced by aripiprazole are more …
Antipsychotic drug—Aripiprazole against schizophrenia, its therapeutic and metabolic effects associated with gene polymorphisms
A Stelmach, K Guzek, A Rożnowska, I Najbar… - Pharmacological …, 2023 - Springer
Second-generation antipsychotics are widely used for the treatment of schizophrenia.
Aripiprazole (ARI) is classified as a third-generation antipsychotic drug with a high affinity for …
Aripiprazole (ARI) is classified as a third-generation antipsychotic drug with a high affinity for …
Impact of the CYP2D6 genotype on steady-state serum concentrations of aripiprazole and dehydroaripiprazole
M Hendset, M Hermann, H Lunde, H Refsum… - European journal of …, 2007 - Springer
Objective Aripiprazole is an atypical antipsychotic drug which is metabolized by the
polymorphic enzyme cytochrome P450 2D6 (CYP2D6). The aim of the present study was to …
polymorphic enzyme cytochrome P450 2D6 (CYP2D6). The aim of the present study was to …
[HTML][HTML] Role of CYP2D6 and CYP3A4 polymorphisms on aripiprazole and dehydroaripiprazole concentrations in patients undergoing long-acting treatment
FJ Toja-Camba, GH Vidal, M Vidal-Villares… - Progress in Neuro …, 2024 - Elsevier
Aripiprazole once-monthly (AOM) exhibits an important interindividual pharmacokinetic
variability with significant implications for its clinical use. CYP2D6 and CYP3A4 highly …
variability with significant implications for its clinical use. CYP2D6 and CYP3A4 highly …
A preliminary study of genetic polymorphisms potentially related to the adverse effects of aripiprazole
K Guzek, A Stelmach, A Rożnowska… - Archives of Pharmacy …, 2023 - archivepp.com
Aripiprazole is an atypical antipsychotic drug that is mainly transformed by the hepatic
enzymes CYP2D6 and CYP3A4. Dose adjustment is recommended for CYP2D6-poor …
enzymes CYP2D6 and CYP3A4. Dose adjustment is recommended for CYP2D6-poor …