OBJECTIVES: Results of pre-post intervention studies of sepsis early warning systems have
been mixed, and randomized clinical trials showing efficacy in the emergency department …

Study objective We identify factors associated with delayed emergency department (ED)
antibiotics and determine feasibility of a 1-hour-from-triage antibiotic requirement in sepsis …

BACKGROUND: The Surviving Sepsis Campaign (SSC) guidelines recommend that broad-
spectrum antibiotics be administered to severely septic patients within 3 h of emergency …

Background Severe sepsis and septic shock are a major health concern worldwide. The
objective of this study is to determine if Severe Sepsis Best Practice Alert (SS-BPA) …

Purpose Pharmacy department contributions to a medical center's broad initiative to improve
sepsis care outcomes are described. Summary Timely and appropriate antimicrobial therapy …

OBJECTIVES: Rapid delivery of antibiotics is a cornerstone of sepsis therapy, although time
targets for specific components of antibiotic delivery are unknown. We quantified time …

Background In 2013, New York began requiring hospitals to follow protocols for the early
identification and treatment of sepsis. However, there is controversy about whether more …

Rationale: Prior sepsis studies evaluating antibiotic timing have shown mixed results.
Objectives: To evaluate the association between antibiotic timing and mortality among …

Background: Studies evaluating the clinical effectiveness of sepsis screening tools and
methods to improve the time from diagnosis to antibiotic administration are needed to …

Objectives: Delayed initiation of appropriate antimicrobials is linked to higher sepsis
mortality. We investigated interphysician variation in septic patients' door-to-antimicrobial …