Enthusiasm for photodynamic therapy (PDT) as a promising technique to eradicate various
cancers has increased exponentially in recent decades. The majority of clinically approved …

Aims: In this study we evaluated temoporfin-loaded polyethylene glycol (PEG) Poly-(d, l-
lactide-co-glycolide)(PLGA) nanoparticles (NPs) as a new formulation for potential use in …

A major challenge in the application of a nanoparticle-based drug delivery system for
anticancer agents is the knowledge of the critical properties that influence their in vivo …

Background Photodynamic therapy (PDT) is photo-treatment of malignant or benign
diseases using photosensitizing agents, light, and oxygen which generates cytotoxic …

Photodynamic therapy (PDT) using oxygen, light, and photosensitizers has been receiving
great attention, because it has potential for making up for the weakness of the existing …

Foscan®, a formulation comprising temoporfin dissolved in a mixture of ethanol and
propylene glycol, has been approved in Europe for palliative photodynamic therapy of …

Temoporfin (mTHPC) represents a very potent second-generation synthetic photosensitizer.
It has shown to be effective in the photodynamic therapy of early or recurrent oral …

The increasing cancer morbidity and mortality requires the development of high-efficiency
and low-toxicity anticancer approaches. In recent years, photodynamic therapy (PDT) has …

Photodynamic therapy (PDT) has developed over last century and is now becoming a more
widely used medical tool having gained regulatory approval for the treatment of various …

Photodynamic therapy (PDT) has emerged as one of the important therapeutic options in
management of cancer and other diseases [M. Triesscheijn, P. Baas, JH Schellens, FA …