Improved photodynamic therapy efficacy of protoporphyrin IX-loaded polymeric micelles using erlotinib pretreatment

L Yan, J Miller, M Yuan, JF Liu, TM Busch… - …, 2017 - ACS Publications
Photodynamic therapy (PDT) has attracted widespread attention in recent years as a
noninvasive and highly selective approach for cancer treatment. We have previously …

Dual-targeting nanosystem for enhancing photodynamic therapy efficiency

J Xu, F Zeng, H Wu, C Yu, S Wu - ACS Applied Materials & …, 2015 - ACS Publications
Photodynamic therapy (PDT) has been recognized as a valuable treatment option for
localized cancers. Herein, we demonstrate a cellular and subcellular targeted strategy to …

Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies

J Xie, Y Wang, W Choi, P Jangili, Y Ge, Y Xu… - Chemical Society …, 2021 - pubs.rsc.org
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …

Recent studies in photodynamic therapy for cancer treatment: From basic research to clinical trials

TE Kim, JE Chang - Pharmaceutics, 2023 - mdpi.com
Photodynamic therapy (PDT) is an emerging and less invasive treatment modality for
various types of cancer. This review provides an overview of recent trends in PDT research …

Nanotechnology-based drug delivery systems for photodynamic therapy of cancer: a review

GMF Calixto, J Bernegossi, LM De Freitas, CR Fontana… - Molecules, 2016 - mdpi.com
Photodynamic therapy (PDT) is a promising alternative approach for improved cancer
treatment. In PDT, a photosensitizer (PS) is administered that can be activated by light of a …

Advances in nanomaterials for photodynamic therapy applications: Status and challenges

J Chen, T Fan, Z Xie, Q Zeng, P Xue, T Zheng, Y Chen… - Biomaterials, 2020 - Elsevier
Photodynamic therapy (PDT), as a non-invasive therapeutic modality that is alternative to
radiotherapy and chemotherapy, is extensively investigated for cancer treatments. Although …

A high therapeutic efficacy of polymeric prodrug nano-assembly for a combination of photodynamic therapy and chemotherapy

X Yi, J Dai, Y Han, M Xu, X Zhang, S Zhen… - Communications …, 2018 - nature.com
Combination of photodynamic therapy and chemotherapy has been emerging as a new
strategy for cancer treatment. Conventional photosensitizer tends to aggregate in aqueous …

Tumor-targeting photodynamic therapy based on folate-modified polydopamine nanoparticles

S Yan, Q Huang, J Chen, X Song, Z Chen… - International Journal …, 2019 - Taylor & Francis
Background Photodynamic therapy (PDT), a clinical anticancer therapeutic modality, has a
long history in clinical cancer treatments since the 1970s. However, PDT has not been …

Features of third generation photosensitizers used in anticancer photodynamic therapy

IS Mfouo-Tynga, LD Dias, NM Inada… - … and photodynamic therapy, 2021 - Elsevier
Cancer remains a main public health issue and the second cause of mortality worldwide.
Photodynamic therapy is a clinically approved therapeutic option. Effective photodynamic …

Development of Novel tetrapyrrole structure Photosensitizers for cancer Photodynamic therapy

N Plekhova, O Shevchenko, O Korshunova… - Bioengineering, 2022 - mdpi.com
The effectiveness of photodynamic therapy (PDT) is based on the triad effects of
photosensitizer (PS), molecular oxygen and visible light on malignant tumors. Such complex …