Could autophagic exhaustion be a final common pathway for podocytopathy in FSGS?

MA Venkatachalam - Journal of the American Society of …, 2015 - journals.lww.com
Among renal syndromes caused by glomerular disorders, FSGS continues to pose the most
challenges in understanding its pathogenesis and therefore, in arriving at mechanism-based …

Management of adult patients with podocytopathies: an update from the ERA Immunonephrology Working Group

S Mirioglu, L Daniel-Fischer, I Berke… - Nephrology Dialysis …, 2024 - academic.oup.com
The histopathological lesions, minimal change disease (MCD) and focal segmental
glomerulosclerosis (FSGS) are entities without immune complex deposits which can cause …

[PDF][PDF] hmad, SH, Ba ema, IM, Bruchfeld,.,… Kronbichler,.(2024)

S Mirioglu, L Daniel-Fischer… - Management of adult … - scholarlypublications …
The histopathological lesions, minimal change disease (MCD) and focal segmental
glomerulosclerosis (FSGS) are entities without immune complex deposits which can cause …

[HTML][HTML] Maximal 'CD80-uria'with minimal change

AD Kistler, J Reiser - Kidney international, 2010 - Elsevier
Differentiation between minimal-change disease and focal segmental glomerulosclerosis
remains challenging, particularly at early stages in children and adults. Garin et al. identify …

[PDF][PDF] Antibody-mediated podocytopathies: a disease entity that implies immunotherapy

A Kronbichler, C Barnini, A Matyjek… - Nephrology Dialysis …, 2024 - oxfordjournals.org
Podocytopathies are kidney diseases in which injury to podocytes, either direct or indirect,
leads to proteinuria [1]. The phenotypic characterization of podocytopathies usually reveals …

Analysis of glomerular deposition of IgM and C3 in patients with podocytopathies

VA Ferreira, CA da Silva, JR do Carmo Neto… - Annals of Diagnostic …, 2024 - Elsevier
Abstract Minimal Change Disease (MCD) and Focal Segmental Glomerulosclerosis (FSGS)
are the main causes of nephrotic syndrome in the world. The complement system appears to …

[PDF][PDF] Outscoring Current Classification Systems for Nephrotic Syndrome

G Hall, J Lin - American Journal of Kidney Diseases, 2022 - academia.edu
Focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) account
for a majority of nephrotic syndrome diagnoses in US adults and children, respectively. 1, 2 …

Defining diagnostic trajectories in patients with podocytopathies

L Cirillo, G Lugli, V Raglianti, F Ravaglia… - Clinical Kidney …, 2022 - academic.oup.com
Podocytopathies are glomerular disorders in which podocyte injury drives proteinuria and
progressive kidney disease. They encompass a broad spectrum of aetiologies, resulting in …

Minimal change disease: Etiology, clinical features, and diagnosis in adults

A Meyrier, J Radhakrishnan… - & Fervenza, FC (Ed.) …, 2022 - uptodate.com
Minimal change disease (MCD) is a major cause of the nephrotic syndrome in children
(approximately 90 percent) and in a minority of adults (approximately 10 percent). MCD and …

Inherited podocytopathies: FSGS and nephrotic syndrome from a genetic viewpoint

MR Pollak - Journal of the American Society of Nephrology, 2002 - journals.lww.com
Recent progress in defining the genetic basis of inherited glomerular disease has helped
illuminate inadequacies in the way we describe many of these diseases. Too often, we talk …