Extracellular matrix (ECM) plays an important role in the development and progression of
atherosclerotic lesions. Changes in the ECM are involved in the pathophysiology of many …

Matrix metalloproteinases (MMPs) are an expanding group of proteolytic enzymes that
participate in numerous physiological and pathological processes including embryogenesis …

Matrix metalloproteinases (MMPs) are a family of zinc metallo-endopeptidases secreted by
cells and are responsible for much of the turnover of matrix components. Several studies …

Matrix metalloproteinases (MMP) are a family of enzymes that selectively digest individual
components of the extracellular matrix. Their function has been studied in both normal …

Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that are regulated by
inflammatory signals to mediate changes in extracellular matrix. Members of the MMP family …

The cardiovascular interstitial space is largely composed of type I and III fibrillar collagens.
Tissue structure, form and function are determined not only by the collagen content but also …

Matrix metalloproteinases (MMP) are a family of zinc-containing endoproteinases that
degrade extracellular matrix (ECM) components. MMP have important roles in the …

Matrix metalloproteinases (MMPs) play an important role in cardiovascular remodeling by
degrading the extracellular matrix. Enhanced MMP expression has been detected in the …

Intimal thickening, the accumulation of cells and extracellular matrix within the inner vessel
wall, is a physiological response to mechanical injury, increased wall stress, or chemical …

Vascular diseases are the main cause of morbidity and mortality. The vascular extracellular
matrix (ECM) is essential in mechanical support, also regulating the cellular behavior …