Multifaceted Alzheimer's disease: Building a roadmap for advancement of novel therapies
D Kaur, T Behl, A Sehgal, S Singh, N Sharma… - Neurochemical …, 2021 - Springer
Alzheimer's disease (AD) is one of the most prevailing neurodegenerative disorders of
elderly humans associated with cognitive damage. Biochemical, epigenetic, and …
elderly humans associated with cognitive damage. Biochemical, epigenetic, and …
Recent advances in the multitarget‐directed ligands approach for the treatment of Alzheimer's disease
With 27 million cases worldwide documented in 2006, Alzheimer's disease (AD) constitutes
an overwhelming health, social, economic, and political problem to nations. Unless a new …
an overwhelming health, social, economic, and political problem to nations. Unless a new …
[HTML][HTML] Multi-targets: An unconventional drug development strategy for Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that eventually leads
to dementia and death of the patient. Despite the enormous amounts of resources and …
to dementia and death of the patient. Despite the enormous amounts of resources and …
Multitarget directed ligand approaches for Alzheimer's disease: A Comprehensive Review
N Ramalakshmi, R RS, N CN - Mini Reviews in Medicinal …, 2021 - ingentaconnect.com
Background: Alzheimer's disease (AD) is a multifactorial neurodegenerative disease, and a
drug which targets a single protein would not provide a cure for this disease. Currently …
drug which targets a single protein would not provide a cure for this disease. Currently …
The multifactorial nature of Alzheimer's disease for developing potential therapeutics
M Carmo Carreiras, E Mendes… - Current topics in …, 2013 - ingentaconnect.com
Alzheimerβs disease (AD) is a multifactorial neurodegenerative disorder with several target
proteins contributing to its aetiology. Pathological, genetic, biochemical, and modeling …
proteins contributing to its aetiology. Pathological, genetic, biochemical, and modeling …
[HTML][HTML] Clinical relevance of biomarkers, new therapeutic approaches, and role of post-translational modifications in the pathogenesis of Alzheimer's disease
I Mumtaz, MO Ayaz, MS Khan, U Manzoor… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder that causes progressive loss of
cognitive functions like thinking, memory, reasoning, behavioral abilities, and social skills …
cognitive functions like thinking, memory, reasoning, behavioral abilities, and social skills …
Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment?
A Rampa, S Gobbi, F Belluti… - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain
associated with memory impairment, progressive cognitive decline and changes in …
associated with memory impairment, progressive cognitive decline and changes in …
[HTML][HTML] Perspective insights into disease progression, diagnostics, and therapeutic approaches in Alzheimer's disease: a judicious update
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the progressive
accumulation of β-amyloid fibrils and abnormal tau proteins in and outside of neurons …
accumulation of β-amyloid fibrils and abnormal tau proteins in and outside of neurons …
Current progress, challenges and future prospects of diagnostic and therapeutic interventions in Alzheimer's disease
K Rajasekhar, T Govindaraju - RSC advances, 2018 - pubs.rsc.org
Alzheimer's disease (AD) is the most prevalent, progressive and multifaceted
neurodegenerative disorder associated with cognition, memory and behavioural …
neurodegenerative disorder associated with cognition, memory and behavioural …
Pathophysiological Aspects and Therapeutic Armamentarium of Alzheimer's Disease: Recent Trends and Future Development
BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …