Alzheimer's disease (AD) is a prevalent neurodegenerative disease characterized by both
amnestic and non-amnestic clinical manifestations. It accounts for approximately 60-70% of …

Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative disorder,
manifested by the loss of memory and cognitive abilities, behavioral disturbance and …

This chapter discusses the rationale for developing multimodal or multifunctional drugs (also
called designed multiple ligands or DMLs) aimed at disease-modifying treatment strategies …

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease. In
humans, AD becomes symptomatic only after brain changes occur over years or decades …

Alzheimer's disease (AD) is a chronic, progressive, and fatal neurodegenerative disorder
affecting cognition, behavior, and function, being one of the most common causes of mental …

Alzheimer's disease is a rather complex neurodegenerative disease, which is attributed to a
combination of multiple factors. Among the many pathological pathways, synaptic …

Alzheimer's disease (AD) is an age-related neurodegenerative disorder that is characterized
by a progressive loss in memory and deterioration of the higher cognitive functions. The …

It has now been~ 30 years since the Alzheimer's disease (AD) research entered what may
be termed the 'molecular era'that began with the identification of the amyloid β protein (Aβ) …

Alzheimer's disease (AD) is the primary cause of dementia in the elderly and one of the
major health problems worldwide. Since its first description by Alois Alzheimer in 1907 …

Alzheimer disease (AD) is biologically defined by the presence of β-amyloid-containing
plaques and tau-containing neurofibrillary tangles. AD is a genetic and sporadic …