Sacubitril/valsartan averts adverse post-infarction ventricular remodeling and preserves systolic function in rabbits

J Torrado, C Cain, AG Mauro, F Romeo… - Journal of the American …, 2018 - jacc.org
Abstract Background: Sacubitril/valsartan (SAC/VAL) is approved by the US Food and Drug
Administration for heart failure with reduced ejection fraction (HFrEF). Objectives: This study …

Sacubitril/valsartan in real-life practice: experience in patients with advanced heart failure and systematic review

C Moliner-Abós, M Rivas-Lasarte… - … drugs and therapy, 2019 - Springer
Purpose Sacubitril/valsartan reduced heart failure (HF) admissions and cardiovascular
mortality in the PARADIGM-HF trial. However, real-life studies are scarce comparing daily …

Reverse Remodeling Effects of Sacubitril-Valsartan: Structural and Functional Optimization in Stage C Heart Failure

S Kalanatari, D Oren, D Medvedofsky, A Narang… - The American Journal of …, 2024 - Elsevier
Sacubitril-valsartan, an angiotensin receptor-neprilysin inhibitor, reduces all-cause mortality
and the rate of heart failure hospitalizations in patients with heart failure with reduced …

[HTML][HTML] Efficacy and safety of sacubitril/valsartan in the treatment of heart failure: Protocol for a systematic review incorporating unpublished clinical study reports

D Byrne, T Fahey, F Moriarty - HRB Open Research, 2020 - ncbi.nlm.nih.gov
Background: Sacubitril/valsartan is a first-in-class angiotensin-receptor neprilysin inhibitor
used to treat heart failure. The evidence for this novel medication is largely based on one …

[HTML][HTML] Efficacy and safety of sacubitril valsartan in treating heart failure with midrange ejection fraction after acute myocardial infarction in diabetic patients

F Ye, H Li, X Chen, Y Wang, W Lin, H Chen, S Huang… - Medicine, 2022 - journals.lww.com
Objective to evaluate the clinical efficacy and safety of sacubitril valsartan in the treatment of
heart failure (HF) with midrange ejection fraction after acute myocardial infarction (AMI) in …

[HTML][HTML] Rationale and methods of the prospective study of biomarkers, symptom improvement, and ventricular remodeling during sacubitril/valsartan therapy for heart …

JL Januzzi, J Butler, E Fombu, A Maisel… - American heart …, 2018 - Elsevier
Background Sacubitril/valsartan is an angiotensin receptor–neprilysin inhibitor indicated for
the treatment of patients with chronic heart failure (HF) with reduced ejection fraction; …

Do the remodeling effects of sacubitril/valsartan treatment depend upon heart failure duration?

A Villani, S Ravaro, P Cerea, S Caravita… - Journal of …, 2020 - journals.lww.com
Aims The angiotensin receptor and neprilysin inhibitor (ARNI) sacubitril/valsartan (LCZ696)
is recommended for the treatment of patients with heart failure in New York Heart …

Efficacy and safety of low‐dose sacubitril/valsartan in heart failure patients: A systematic review and meta‐analysis

WW Chen, J Jiang, J Gao, XZ Zhang, YM Li… - Clinical …, 2023 - Wiley Online Library
Background Controversy has persisted over the clinical benefits of low‐dose
sacubitril/valsartan in patients with heart failure (HF). Hypothesis Low‐dose …

[HTML][HTML] The effect of sacubitril/valsartan on cardiac function and cardiac remodeling in patients with heart failure with reduced ejection fraction

F Chen, G Tian, X Bai, J Li… - Annals of Palliative …, 2021 - apm.amegroups.org
Background: The aim of this study was to observe the effect of Sacubitril/Valsartan on
cardiac function and remodeling in patients with heart failure with reduced ejection fraction …

[HTML][HTML] Efficacy of sacubitril valsartan sodium tablet for the treatment of chronic heart failure: A systematic review protocol of randomized controlled trials

Z Liu, J Wang, Y Li - Medicine, 2019 - journals.lww.com
Background: This study aims to systematically explore the efficacy of sacubitril valsartan
sodium tablet (SVST) for the treatment of chronic heart failure (CHF). Methods: Nine …