Contribution of ATPase copper transporters in animal but not plant virulence of the crossover pathogen Aspergillus flavus
The ubiquitous fungus Aspergillus flavus is notorious for contaminating many important
crops and food-stuffs with the carcinogenic mycotoxin, aflatoxin. This fungus is also the …
crops and food-stuffs with the carcinogenic mycotoxin, aflatoxin. This fungus is also the …
The Aspergillus fumigatus transcription factor AceA is involved not only in Cu but also in Zn detoxification through regulating transporters CrpA and ZrcA
Z Cai, W Du, Z Zhang, L Guan, Q Zeng… - Cellular …, 2018 - Wiley Online Library
Abstract Copper (Cu) and zinc (Zn) are essential nutrients for both pathogens and hosts;
however, their excess accumulation is toxic for all cells. The Aspergillus transcription factor …
however, their excess accumulation is toxic for all cells. The Aspergillus transcription factor …
Heavy Metal-Induced Expression of PcaA Provides Cadmium Tolerance to Aspergillus fumigatus and Supports Its Virulence in the Galleria mellonella Model
F Bakti, C Sasse, T Heinekamp, I Pócsi… - Frontiers in …, 2018 - frontiersin.org
Most of the metal transporters in Aspergillus fumigatus are yet uncharacterized. Their role in
fungal metabolism and virulence remains unclear. This paper describes the novel P IB-type …
fungal metabolism and virulence remains unclear. This paper describes the novel P IB-type …
Transcriptional response of Aspergillus fumigatus to copper and the role of the Cu chaperones
D Anabosi, Z Meir, Y Shadkchan, M Handelman… - Virulence, 2021 - Taylor & Francis
Aspergillus fumigatus is the leading cause of life-threatening invasive mold infections in
immunocompromised individuals. This ubiquitous saprophyte possesses several natural …
immunocompromised individuals. This ubiquitous saprophyte possesses several natural …
Cu-sensing transcription factor Mac1 coordinates with the Ctr transporter family to regulate Cu acquisition and virulence in Aspergillus fumigatus
Z Cai, W Du, Q Zeng, N Long, C Dai, L Lu - Fungal Genetics and Biology, 2017 - Elsevier
Copper (Cu) is an essential trace element and is regarded as an important virulence factor
in fungal pathogens. Previous studies suggest that a putative Cu-sensing transcription factor …
in fungal pathogens. Previous studies suggest that a putative Cu-sensing transcription factor …
Ambient Availability of Amino Acids, Proteins, and Iron Impacts Copper Resistance of Aspergillus fumigatus
A Yap, H Talasz, H Lindner, R Würzner… - Frontiers in Cellular and …, 2022 - frontiersin.org
The transition metals iron and copper are required by virtually all organisms but are toxic in
excess. Acquisition of both metals and resistance to copper excess have previously been …
excess. Acquisition of both metals and resistance to copper excess have previously been …
Cu transporter protein CrpF protects against Cu-induced toxicity in Fusarium oxysporum
D Lorenzo-Gutiérrez, L Gómez-Gil, J Guarro… - Virulence, 2020 - Taylor & Francis
Cu is an essential trace element for cell growth and proliferation. However, excess of Cu
accumulation leads to cellular toxicity. Thus, precise and tight regulation of Cu homeostasis …
accumulation leads to cellular toxicity. Thus, precise and tight regulation of Cu homeostasis …
Transcription factor Afmac1 controls copper import machinery in Aspergillus fumigatus
Y Kusuya, D Hagiwara, K Sakai, T Yaguchi, T Gonoi… - Current Genetics, 2017 - Springer
Copper (Cu) is an essential metal for all living organisms, although it is toxic in excess.
Filamentous fungus must acquire copper from its environment for growth. Despite its …
Filamentous fungus must acquire copper from its environment for growth. Despite its …
The Role of Zinc in Copper Homeostasis of Aspergillus fumigatus
S Kang, H Seo, HS Moon, JH Kwon, YS Park… - International journal of …, 2020 - mdpi.com
Copper is an essential metal ion that performs many physiological functions in living
organisms. Deletion of Afmac1, which is a copper-responsive transcriptional activator in A …
organisms. Deletion of Afmac1, which is a copper-responsive transcriptional activator in A …
Copper Utilization, Regulation, and Acquisition by Aspergillus fumigatus
Copper is an essential micronutrient for the opportunistic human pathogen, Aspergillus
fumigatus. Maintaining copper homeostasis is critical for survival and pathogenesis. Copper …
fumigatus. Maintaining copper homeostasis is critical for survival and pathogenesis. Copper …