Brugada syndrome and arrhythmogenic cardiomyopathy: overlapping disorders of the connexome?

Y Ben-Haim, A Asimaki, ER Behr - EP Europace, 2021 - academic.oup.com
Arrhythmogenic cardiomyopathy (ACM) and Brugada syndrome (BrS) are inherited diseases
characterized by an increased risk for arrhythmias and sudden cardiac death. Possible …

Unmasking the molecular link between arrhythmogenic cardiomyopathy and Brugada syndrome

J Moncayo-Arlandi, R Brugada - Nature Reviews Cardiology, 2017 - nature.com
The intercalated discs that connect cardiomyocytes control cell-to-cell adhesion and
communication. Several macromolecular structures (desmosomes, fascia adherens …

Structural heart alterations in Brugada syndrome: is it really a channelopathy? A systematic review

A Oliva, S Grassi, V Pinchi, F Cazzato, M Coll… - Journal of Clinical …, 2022 - mdpi.com
Brugada syndrome (BrS) is classified as an inherited cardiac channelopathy attributed to
dysfunctional ion channels and/or associated proteins in cardiomyocytes rather than to …

[HTML][HTML] Arrhythmogenic cardiomyopathy and Brugada syndrome: diseases of the connexome

E Agullo-Pascual, M Cerrone, M Delmar - FEBS letters, 2014 - Elsevier
This review summarizes data in support of the notion that the cardiac intercalated disc is the
host of a protein interacting network, called “the connexome”, where molecules classically …

The Brugada syndrome: a rare arrhythmia disorder with complex inheritance

JB Gourraud, J Barc, A Thollet… - Frontiers in …, 2016 - frontiersin.org
For the last 10 years, applying new sequencing technologies to thousands of whole exomes
has revealed the high variability of the human genome. Extreme caution should thus be …

Is early sudden death in the course of arrhythmogenic cardiomyopathy due to initial Brugada syndrome?

S Peters - International Journal of Cardiology, 2015 - internationaljournalofcardiology.com
The early course of arrhythmogenic cardiomyopathy is sometimes characterised by sudden
cardiac death due to primary electrical disease before structural disease becomes evident …

Worse prognosis in Brugada syndrome patients with arrhythmogenic cardiomyopathy features

E Scheirlynck, M Chivulescu, ØH Lie, A Motoc… - Clinical …, 2020 - jacc.org
Objectives This study aimed to assess the presence of echocardiographic and
electrocardiographic similarities in patients with Brugada syndrome (BrS) and …

Arrhythmogenesis in Brugada syndrome: impact and constrains of current concepts

M Bébarová - International journal of cardiology, 2013 - Elsevier
Brugada syndrome (BrS), an inherited arrhythmogenic disease first described in 1992, is
characterized by ST segment elevations on the electrocardiogram in the right precordium …

Right ventricular electromechanical abnormalities in Brugada syndrome: is this a cardiomyopathy?

C Pappone, MM Monasky, E Micaglio… - European Heart …, 2020 - academic.oup.com
Brugada syndrome (BrS) has been often described as a purely electrical disease. However,
current dogma surrounding this concept has shifted to accept that BrS is associated with …

Brugada syndrome: update and future perspectives

EMJ Marsman, PG Postema, CA Remme - Heart, 2022 - heart.bmj.com
Brugada syndrome (BrS) is an inherited cardiac disorder, characterised by a typical ECG
pattern and an increased risk of arrhythmias and sudden cardiac death (SCD). BrS is a …