Biophysical characterization of the underappreciated and important relationship between heart rate variability and heart rate

O Monfredi, AE Lyashkov, AB Johnsen, S Inada… - …, 2014 - Am Heart Assoc
Heart rate (HR) variability (HRV; beat-to-beat changes in the R-wave to R-wave interval) has
attracted considerable attention during the past 30+ years (PubMed currently lists> 17 000 …

Heart rate variability in systemic hypertension

HV Huikuri, A Ylitalo, SM Pikkujämsä… - The American journal of …, 1996 - Elsevier
Low heart rate (HR) variability is a risk factor for cardiac mortality in various patient
populations, but it has not been well established whether patients with long-standing …

Reduced heart rate variability and new-onset hypertension: insights into pathogenesis of hypertension: the Framingham Heart Study

JP Singh, MG Larson, H Tsuji, JC Evans… - …, 1998 - Am Heart Assoc
Heart rate variability (HRV) is a useful noninvasive tool to assess cardiac autonomic
function. The purpose of this study was to (1) compare measures of HRV between …

Measurement of heart rate variability: a clinical tool or a research toy?

HV Huikuri, T Mäkikallio, KEJ Airaksinen… - Journal of the American …, 1999 - jacc.org
OBJECTIVES The objectives of this review are to discuss the diversity of mechanisms that
may explain the association between heart rate (HR) variability and mortality, to appraise the …

Role of elevated heart rate in the development of cardiovascular disease in hypertension

P Palatini - Hypertension, 2011 - Am Heart Assoc
That elevated heart rate (HR) is a risk factor for cardiovascular morbidity and mortality in
healthy people as well as in patients with cardiac diseases is supported by numerous …

Twenty-four hour time domain heart rate variability and heart rate: relations to age and gender over nine decades

K Umetani, DH Singer, R McCraty… - Journal of the American …, 1998 - jacc.org
Objectives. This study sought to define the effects of age and gender effects on the normal
range of time domain heart rate variability (HRV) over nine decades in healthy subjects …

[HTML][HTML] Heart rate variability–a historical perspective

GE Billman - Frontiers in physiology, 2011 - frontiersin.org
Heart rate variability (HRV), the beat-to-beat variation in either heart rate or the duration of
the R–R interval–the heart period, has become a popular clinical and investigational tool …

[HTML][HTML] Inverse correlation between heart rate variability and heart rate demonstrated by linear and nonlinear analysis

SZH Kazmi, H Zhang, W Aziz, O Monfredi, SA Abbas… - PloS one, 2016 - journals.plos.org
The dynamical fluctuations in the rhythms of biological systems provide valuable information
about the underlying functioning of these systems. During the past few decades analysis of …

Resting heart rate pattern during follow-up and mortality in hypertensive patients

L Paul, CE Hastie, WS Li, C Harrow, S Muir… - …, 2010 - Am Heart Assoc
There is a linear relationship between resting heart rate (HR) and mortality in normotensive
and untreated hypertensive individuals. However, it is not clear whether HR is a marker of …

[HTML][HTML] An introduction to heart rate variability: methodological considerations and clinical applications

GE Billman, HV Huikuri, J Sacha, K Trimmel - Frontiers in physiology, 2015 - frontiersin.org
Heart rate variability (HRV), the beat-to-beat variation in either heart rate or the duration of
the RR interval, has become a popular clinical and investigational tool (Task Force of the …