Cardiotoxicity of fluoropyrimidines: epidemiology, mechanisms, diagnosis, and management

M Jurczyk, M Król, A Midro, M Kurnik-Łucka… - Journal of Clinical …, 2021 - mdpi.com
Cancer is a growing public health problem; it is responsible annually for millions of deaths
worldwide. Fluoropyrimidines are highly effective and commonly prescribed anti-neoplastic …

[HTML][HTML] Fluoropyrimidine-induced cardiotoxicity

AL Deac, CC Burz, IC Bocsan… - World Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
Cardio-oncology is a discipline based on early screening, monitoring, and treating
chemotherapy-induced cardiotoxicity. There are many chemotherapeutics known for their …

Cardiotoxicities of 5-fluorouracil and other fluoropyrimidines

T Shiga, M Hiraide - Current treatment options in oncology, 2020 - Springer
Opinion statement Fluoropyrimidine (FP) is used to treat a wide range of cancers; however, it
is associated with drug-induced vascular toxicity, as well as angina pectoris and coronary …

Fluoropyrimidine-associated cardiotoxicity

J Kanduri, LA More, A Godishala… - Cardiology …, 2019 - cardiology.theclinics.com
The fluoropyrimidines, namely 5-fluorouracil (5-FU) and its oral prodrug, capecitabine, are
the third most commonly used chemotherapeutic agents for the treatment of solid tumors of …

Fluoropyrimidine-induced cardiotoxicity: manifestations, mechanisms, and management

ME Layoun, CD Wickramasinghe, MV Peralta… - Current oncology …, 2016 - Springer
Abstract Fluoropyrimidines—5-fluorouracil (5-FU) and capecitabine—have been implicated
as cardiotoxic chemotherapy agents. This rare, albeit potentially serious toxicity has been …

5-fluorouracil and cardiotoxicity: a review

JD Sara, J Kaur, R Khodadadi… - … in medical oncology, 2018 - journals.sagepub.com
Fluoropyrimidines such as 5-fluorouracil (5-FU) form the foundation of a wide variety of
chemotherapy regimens. 5-FU is in fact the third most commonly used chemotherapeutic …

Fluoropyrimidine‐associated cardiotoxicity: A retrospective case‐control study

I Raber, S Warack, J Kanduri, A Pribish… - The …, 2020 - academic.oup.com
Abstract Background The fluoropyrimidines, 5‐fluorouracil (5‐FU) and capecitabine, are
commonly used chemotherapeutic agents that have been associated with coronary …

Management of fluoropyrimidine-induced cardiac adverse outcomes following cancer treatment

M Rajaeinejad, P Parhizkar-Roudsari… - Cardiovascular …, 2024 - Springer
Advancements in cancer treatments have improved survival rates but have also led to
increased cardiotoxicities, which can cause adverse cardiovascular events or worsen pre …

Cardiotoxicity of fluoropyrimidines in different schedules of administration: a prospective study

C Kosmas, MS Kallistratos, P Kopterides… - Journal of cancer …, 2008 - Springer
Abstract Background Cardiotoxicity associated with 5-Fluorouracil (5FU) administration has
been infrequently reported in literature, albeit various series of acute coronary syndromes …

Fluoropyrimidine-induced cardiotoxicity

I Depetris, D Marino, A Bonzano, C Cagnazzo… - Critical reviews in …, 2018 - Elsevier
Abstract Fluoropyrimidines (5-fluorouracil and capecitabine) are antimetabolite drugs,
widely used for the treatment of a variety of cancers, both in adjuvant and in metastatic …