MicroRNAs and natural compounds mediated regulation of TGF signaling in prostate cancer

Z Javed, K Khan, A Rasheed, H Sadia… - Frontiers in …, 2021 - frontiersin.org
Prostate cancer (PCa) is with rising incidence in male population globally. It is a complex
anomaly orchestrated by a plethora of cellular processes. Transforming growth factor-beta …

microRNA and non-canonical TGF-β signalling: Implications for prostate cancer therapy

E Ottley, E Gold - Critical Reviews in Oncology/Hematology, 2014 - Elsevier
The incidence of prostate cancer is increasing worldwide and marks a significant health
issue. Paired with this, current therapeutic options for advanced prostate cancer, notably …

A review of the biological role of miRNAs in prostate cancer suppression and progression

AS Doghish, A Ismail, HA El-Mahdy, MA Elkady… - International journal of …, 2022 - Elsevier
Prostate cancer (PC) is the third-leading cause of cancer-related deaths worldwide.
Although the current treatment strategies are progressing rapidly, PC is still representing a …

MicroRNA mediated therapeutic effects of natural agents in prostate cancer

K Anjaly, AB Tiku - Molecular Biology Reports, 2021 - Springer
Background Several natural products, extensively studied for their anticancer activities, have
been found to play an efficient role in preventing prostate cancer (PCa). Recently many …

Restoring TGFβ1 pathway-related microRNAs: possible impact in metastatic prostate cancer development

JI Santos, AL Teixeira, F Dias, M Gomes, A Nogueira… - Tumor Biology, 2014 - Springer
In developed countries, prostate cancer (PC) is the neoplasia more frequently diagnosed in
men. The signaling pathway induced by the transforming growth factor β1 (TGFβ1) has an …

Targeting androgen receptor signaling with MicroRNAs and Curcumin: a promising therapeutic approach for Prostate Cancer Prevention and intervention

Z Javed, K Khan, A Rasheed, H Sadia… - Cancer cell …, 2021 - Springer
Prostate cancer (PC) is a multifactorial disease characterized by the abrogation of androgen
receptor signaling. Advancement in microbiology techniques has highlighted the significant …

TGF-β1-regulated miR-3691-3p targets E2F3 and PRDM1 to inhibit prostate cancer progression

YM Hu, XL Lou, BZ Liu, L Sun, S Wan… - Asian Journal of …, 2021 - journals.lww.com
Transforming growth factor-β1 (TGF-β1) acts as a tumor promoter in advanced prostate
cancer (PCa). We speculated that microRNAs (miRNAs) that are inhibited by TGF-β1 might …

Missing link between microRNA and prostate cancer

BS Gill, JM Alex, Navgeet, S Kumar - Tumor Biology, 2016 - Springer
MicroRNAs are the non-coding RNAs which regulate endogenous gene expression in
animal and plant cells. Alterations in the level of micro-ribonucleic acids (miRNAs) involving …

Mirnas as therapeutic tools and biomarkers for prostate cancer

N Arrighetti, GL Beretta - Pharmaceutics, 2021 - mdpi.com
Prostate cancer (PCa) is the fifth cause of tumor-related deaths in man worldwide. Despite
the considerable improvement in the clinical management of PCa, several limitations …

Diagnostic, Prognostic and Theranostic Potential of miRNAs in Prostate Cancer

A Savic-Radojevic, M Pljesa-Ercegovac - Prostate Cancer: Advancements …, 2024 - Springer
A novel class of gene regulators, small noncoding RNAs or microRNAs (miRNAs) has an
important role in various malignancies, including prostate cancer (PCa). Contribution of …