The novel coronavirus disease COVID-19 originates in the lungs, but it may extend to other
organs, causing, in severe cases, multiorgan damage, including cardiac injury and acute …

In a stunningly short period of time, the unexpected coronavirus disease 2019 (COVID-19)
pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2), has …

Acute respiratory failure and a systemic coagulopathy are critical aspects of the morbidity
and mortality characterizing infection with severe acute respiratory distress syndrome …

Most patients who became critically ill following infection with COVID-19 develop severe
acute respiratory syndrome (SARS) attributed to a maladaptive or inadequate immune …

Complement plays an important role in the direct defense to pathogens, but can also
activate immune cells and the release of pro-inflammatory cytokines. However, in critically ill …

Increased levels of circulating complement activation products have been reported in COVID-
19 patients, but only limited information is available on complement involvement at the …

The outbreak of COVID-19 disease, caused by SARS-CoV-2 beta-coronovirus, urges a
focused search for the underlying mechanisms and treatment options. The lung is the major …

Abstract Coronavirus disease of 2019 (COVID-19) is a highly contagious respiratory
infection that is caused by the severe acute respiratory syndrome coronavirus 2. Although …

Increasing evidence suggests that activation of the complement system plays a key role in
the pathogenesis and disease severity of Coronavirus disease 2019 (COVID-19). We used a …

Lung inflammation and damage is prominent in people infected with SARS-Cov-2 and a
major determinant of morbidity and mortality. We report the deposition of complement …