The non-replicating persistence (NRP) phenotype of Mycobacterium tuberculosis (NRP-TB)
is assumed to be responsible for the maintenance of latent infection and the requirement of …

Defence against oxidative stress is crucial for Mycobacterium tuberculosis to survive and
replicate within macrophages. Mycobacteria have evolved multilayer antioxidant systems …

Mycobacterium tuberculosis (Mtb) infections cause tuberculosis (TB), an infectious disease
which causes∼ 1.5 million deaths annually. The ability of this pathogen to evade, escape …

Bacterial pathogens have sophisticated systems that allow them to survive in hosts in which
innate immunity is the frontline of defense. One of the substances produced by infected …

Members of the Mycobacterium tuberculosis complex (MTBC) show distinct host
adaptations, preferences and phenotypes despite being> 99% identical at the nucleic acid …

Mycobacterium avium subsp. paratuberculosis causes an enteric infection in cattle, with a
great impact on the dairy industry in the United States and worldwide. Characterizing the …

Mycobacteria encounter a number of environmental changes during infection and respond
using different mechanisms. Small RNA (sRNA) is a post-transcriptionally regulatory system …

Pseudomonas aeruginosa is a ubiquitous Gram-negative pathogen known to inhabit
hypoxic mucus plugs of cystic fibrosis (CF) patient lungs. Despite the high prevalence and …

Abstract Background Non-toxigenic Corynebacterium diphtheriae strains are emerging as a
major cause of severe pharyngitis and tonsillitis as well as invasive diseases such as …

Understanding how Mycobacterium tuberculosis has evolved into a professional pathogen
is helpful in studying its pathogenesis and for designing vaccines. We investigated how the …