Efficient priming of CD4 T cells by Langerin-expressing dendritic cells targeted with porcine epidemic diarrhea virus spike protein domains in pigs

S Subramaniam, D Cao, D Tian, QM Cao, C Overend… - Virus research, 2017 - Elsevier
Porcine epidemic diarrhea virus (PEDV) first emerged in the United States in 2013 causing
high mortality and morbidity in neonatal piglets with immense economic losses to the swine …

Vaccination of sows with a dendritic cell-targeted porcine epidemic diarrhea virus S1 protein-based candidate vaccine reduced viral shedding but exacerbated gross …

S Subramaniam, DM Yugo… - Journal of General …, 2018 - microbiologyresearch.org
Porcine epidemic diarrhea virus (PEDV) poses a serious threat to swine worldwide as
evidenced by its recent introduction into the USA and the devastating economic impact it …

[HTML][HTML] Oral recombinant Lactobacillus vaccine targeting the intestinal microfold cells and dendritic cells for delivering the core neutralizing epitope of porcine …

S Ma, L Wang, X Huang, X Wang, S Chen, W Shi… - Microbial Cell …, 2018 - Springer
Background Porcine epidemic diarrhea caused by porcine epidemic diarrhea virus (PEDV)
has led to serious economic losses to the swine industry worldwide. In this study, an oral …

[HTML][HTML] Oral delivery of maize-produced porcine epidemic diarrhea virus spike protein elicits neutralizing antibodies in pigs

E Egelkrout, C Hayden, G Fake, T Keener… - Plant Cell, Tissue and …, 2020 - Springer
Abstract Porcine Epidemic Diarrhea Virus (PEDV) causes severe diarrhea and mortality in
piglets. Robust immunity may break the transmission cycle. Expression of antigens in maize …

[HTML][HTML] Oral Immunization against PEDV with Recombinant Lactobacillus casei Expressing Dendritic Cell-Targeting Peptide Fusing COE Protein of PEDV in Piglets

X Hou, X Jiang, Y Jiang, L Tang, Y Xu, X Qiao, M Liu… - Viruses, 2018 - mdpi.com
Porcine epidemic diarrhea (PED) is a highly contagious disease in newborn piglets. In our
previous study, a genetically engineered Lactobacillus casei oral vaccine (pPG-COE …

[HTML][HTML] Oral delivery of probiotics expressing dendritic cell-targeting peptide fused with porcine epidemic diarrhea virus COE antigen: a promising vaccine strategy …

X Wang, L Wang, X Huang, S Ma, M Yu, W Shi, X Qiao… - Viruses, 2017 - mdpi.com
Porcine epidemic diarrhea virus (PEDV), an enteric coronavirus, is the causative agent of
porcine epidemic diarrhea (PED) that damages intestinal epithelial cells and results in …

[HTML][HTML] Porcine epidemic Diarrhea Virus envelope protein blocks SLA-DR expression in barrow-derived dendritic cells by inhibiting promoters activation

J Wang, Y Wang, B Liu, Y He, Z Li, Q Zhao… - Frontiers in …, 2021 - frontiersin.org
Porcine epidemic diarrhea (PED) is an acute, highly contagious intestinal swine disease
caused by porcine epidemic diarrhea virus (PEDV). In addition to known PEDV infection …

[HTML][HTML] Immune Responses in Pregnant Sows Induced by Recombinant Lactobacillus johnsonii Expressing the COE Protein of Porcine Epidemic Diarrhea Virus …

D Zheng, X Wang, N Ju, Z Wang, L Sui, L Wang, X Qiao… - Viruses, 2021 - mdpi.com
Porcine epidemic diarrhea (PED) induced by porcine epidemic diarrhea virus (PEDV) is an
intestinal infectious disease in pigs that causes serious economic losses to the pig industry …

Cell attenuated porcine epidemic diarrhea virus strain Zhejiang08 provides effective immune protection attributed to dendritic cell stimulation

Y Li, G Wang, J Wang, K Man, Q Yang - Vaccine, 2017 - Elsevier
Since 2010, the porcine epidemic diarrhea coronavirus (PEDV) has caused significant
damage to the global pork industry. However, classical PEDV vaccine strains only provide …

[HTML][HTML] Adenovirus vector-mediated single chain variable fragments target the nucleocapsid protein of porcine epidemic diarrhea virus and protect against viral …

F Wang, Q Zhang, F Zhang, E Zhang, M Li… - Frontiers in …, 2023 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) mainly infects the intestinal epithelial cells of pigs,
causing porcine epidemic diarrhea (PED). In particular, the virus causes severe diarrhea …