Bacteria growing in biofilms often develop multicellular, three-dimensional structures known
as microcolonies. Complex differentiation within biofilms of Pseudomonas aeruginosa …

Mature Pseudomonas aeruginosa biofilms undergo specific developmental events. Using a
bacteriophage mutant, generated by deletion of the entire filamentous Pf4 prophage, we …

ABSTRACT A current question in biofilm research is whether biofilm-specific genetic
processes can lead to differentiation in physiology and function among biofilm cells. In …

Detailed knowledge of the developmental process from single cells scattered on a surface to
complex multicellular biofilm structures is essential in order to create strategies to control …

Bacteria are capable of forming elaborate multicellular communities called biofilms. Pattern
formation in biofilms depends on cell proliferation and cellular migration in response to the …

The survival of bacteria in nature is greatly enhanced by their ability to grow within surface-
associated communities called biofilms. Commonly, biofilms generate proliferations of …

Biofilm formation by Pseudomonas aeruginosa is hypothesized to follow a developmental
pattern initiated by attachment to a surface followed by microcolony formation and mature …

Pseudomonas aeruginosa is a pathogenic bacterium widely investigated for its high
incidence in clinical environments and its ability to form strong biofilms. During biofilm …

There is growing evidence that Pseudomonas aeruginosa biofilms exhibit a multicellular
developmental life cycle analogous to that of the myxobacteria. In non-mucoid PAO1 …

Surface-associated microbial communities in many cases display dynamic developmental
patterns. Model biofilms formed by Pseudomonas aeruginosa and Pseudomonas putida in …