Advances and challenges in geroscience research: an update

A Yabluchanskiy, Z Ungvari, A Csiszar… - Physiology …, 2018 - akjournals.com
Aging remains the most pervasive risk factor for a wide range of chronic diseases that afflict
modern societies. In the United States alone, incidence of age-related diseases (eg …

Advances in geroscience: impact on healthspan and chronic disease

JB Burch, AD Augustine, LA Frieden… - … Series A: Biomedical …, 2014 - academic.oup.com
Population aging is unprecedented, without parallel in human history, and the 21st century
will witness even more rapid aging than did the century just past. Improvements in public …

Advances in geroscience

F Sierra, R Kohanski - 2016 - Springer
Geroscience is a new field that aims to bridge two communities: biologists focused on
understanding the basic mechanisms that drive aging, and geriatricians attempting to …

The emergence of geroscience as an interdisciplinary approach to the enhancement of health span and life span

F Sierra - Cold Spring Harbor perspectives in …, 2016 - perspectivesinmedicine.cshlp.org
Research on the biology of aging has accelerated rapidly in the last two decades. It is now at
the point where translation of the findings into useful approaches to improve the health of the …

Healthy aging: the ultimate preventative medicine

M Kaeberlein, PS Rabinovitch, GM Martin - Science, 2015 - science.org
Age is the greatest risk factor for nearly every major cause of mortality in developed nations.
Despite this, most biomedical research focuses on individual disease processes without …

Geroscience and the trans-NIH geroscience interest group, GSIG

F Sierra, R Kohanski - Geroscience, 2017 - Springer
Age is by far the major risk factor for most chronic diseases. This has been common
knowledge since time immemorial. Aging encompasses the biological changes most often …

Geroscience for the next chapter of medicine

G Duque, LA Lipsitz, L Ferrucci, S Addie… - The Journals of …, 2023 - academic.oup.com
In 1863, Rudolph Virchow published “Cellular Pathology as Based upon Physiological and
Pathological Histology,” establishing for the first time that cellular pathology was tightly …

Moving geroscience into uncharted waters

F Sierra - Journals of Gerontology Series A: Biomedical …, 2016 - academic.oup.com
Research into the basic biology of aging has undergone a seismic shift in the last 10–20
years, moving rapidly from the very descriptive approach focused on the aged that was the …

A gerophysiology perspective on healthy ageing

PH Kemoun, I Ader, V Planat-Benard, C Dray… - Ageing research …, 2022 - Elsevier
Improvements in public health and health care have resulted in significant increases in
lifespan globally, but also in a significant increase in chronic disease prevalence. This has …

GeroScience: understanding the interaction of processes of aging and chronic diseases

WE Sonntag, Z Ungvari - Age, 2016 - Springer
After careful deliberation, the American Aging Association (AAA) has decided to change the
title of its journal from AGE to GeroScience, effective January 2017. This title change is …