Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

Mesenchymal stem cells (MSCs), whose mechanism of action is predominantly paracrine,
are being widely tested for the treatment of a variety of human diseases. No one factor has …

Exosomes are tiny vesicles with a double membrane structure that cells produce. They
range in diameter from 40 to150 nm and may contain a variety of biomolecules including …

Exosomes are small membrane vesicles secreted by most cell types, and widely exist in cell
supernatants and various body fluids. They can transmit numerous bioactive elements, such …

Stem cells can be used for regenerative medicine and as treatments for disease. The
application of tissue engineering-related transplantation, stem cells, and local changes in …

Mesenchymal stem cells (MSCs) have been demonstrated to have a great potential in the
treatment of several diseases due to their differentiation and immunomodulatory capabilities …

Tissue regeneration by stem cells is driven by the paracrine activity of shedding vesicles and
exosomes, which deliver specific cargoes to the recipient cells. Proteins, RNA, cytokines and …

Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …

MSCs are an extensively used cell type in clinical trials today. The initial rationale for their
clinical testing was based on their differentiation potential. However, the lack of correlation …

Over the last few decades, mesenchymal stem cells-derived exosomes (MSCs-Ex) have
attracted a lot of attention as a therapeutic tool in regenerative medicine. Exosomes are …