New autoimmune diseases after autologous hematopoietic stem cell transplantation for multiple sclerosis

RK Burt, PA Muraro, D Farge, MC Oliveira… - Bone Marrow …, 2021 - nature.com
Abstract Secondary autoimmune diseases (2ndADs), most frequently autoimmune
cytopenias (AICs), were first described after allogeneic hematopoietic stem cell …

Development of a secondary autoimmune disorder after hematopoietic stem cell transplantation for autoimmune diseases: role of conditioning regimen used

Y Loh, Y Oyama, L Statkute, K Quigley, K Yaung… - Blood, 2007 - ashpublications.org
Patients undergoing autologous hematopoietic stem cell transplantation (auto-HSCT) for
autoimmune disease may have an added propensity to develop a second autoimmune …

B-cell reconstitution after autologous hematopoietic stem cell transplantation in multiple sclerosis

V von Niederhäusern, J Ruder, M Ghraichy… - Neurology …, 2022 - AAN Enterprises
Background and Objectives Autologous hematopoietic stem cell transplantation (aHSCT) is
increasingly used to treat aggressive forms of multiple sclerosis (MS). This procedure is …

Immune reconstitution following autologous hematopoietic stem cell transplantation for multiple sclerosis: a review on behalf of the EBMT autoimmune diseases …

MT Cencioni, A Genchi, G Brittain, TI de Silva… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a central nervous system (CNS) disorder, which is mediated by an
abnormal immune response coordinated by T and B cells resulting in areas of inflammation …

Haematopoietic stem cell transplantation results in extensive remodelling of the clonal T cell repertoire in multiple sclerosis

J Massey, K Jackson, M Singh, B Hughes… - Frontiers in …, 2022 - frontiersin.org
Autologous haematopoietic stem cell transplantation (AHSCT) is a vital therapeutic option
for patients with highly active multiple sclerosis (MS). Rates of remission suggest AHSCT is …

Immunological correlates of favorable long-term clinical outcome in multiple sclerosis patients after autologous hematopoietic stem cell transplantation

LCM Arruda, JTC de Azevedo, GLV de Oliveira… - Clinical …, 2016 - Elsevier
High dose immunosuppression followed by autologous hematopoietic stem cell
transplantation (AHSCT) induces prolonged clinical remission in multiple sclerosis (MS) …

Autologous haematopoietic stem cell transplantation reduces abnormalities in the expression of immune genes in multiple sclerosis

APA Sousa, KCR Malmegrim, RA Panepucci… - Clinical …, 2015 - portlandpress.com
Autologous haematopoietic stem-cell transplantation (AHSCT) has been experimented as a
treatment in patients affected by severe forms of multiple sclerosis (MS) who failed to …

Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation

FG Karnell, D Lin, S Motley, T Duhen… - Clinical & …, 2017 - academic.oup.com
Multiple sclerosis is an inflammatory T cell-mediated autoimmune disease. In a Phase II
clinical trial, high-dose immunosuppressive therapy combined with autologous CD34+ …

Dynamics of T cell repertoire renewal following autologous hematopoietic stem cell transplantation in multiple sclerosis

J Ruder, MJ Docampo, J Rex, S Obahor… - Science Translational …, 2022 - science.org
Autologous hematopoietic stem cell transplantation (aHSCT) is a highly effective treatment
of multiple sclerosis (MS). It depletes autoreactive cells and subsequently renews adaptive …

Sustained immunotolerance in multiple sclerosis after stem cell transplant

M Visweswaran, K Hendrawan… - Annals of Clinical …, 2022 - Wiley Online Library
Objective Autologous haematopoietic stem cell transplantation (AHSCT) has the potential to
induce sustained periods of disease remission in multiple sclerosis (MS), which is an …