Low dose shikonin and anthracyclines coloaded liposomes induce robust immunogenetic cell death for synergistic chemo-immunotherapy

J Li, S Zhou, J Yu, W Cai, Y Yang, X Kuang… - Journal of Controlled …, 2021 - Elsevier
Chemo-immunotherapy based on immunogenic cell death (ICD) is a promising strategy for
cancer therapy. However, the effective ICD requires a high dosage of ICD stimulus, which …

Nanotechnology-enabled immunogenic cell death for improved cancer immunotherapy

W Li, Y Jiang, J Lu - International journal of pharmaceutics, 2023 - Elsevier
Tumor immunotherapy has revolutionized the field of oncology treatments in recent years.
As one of the promising strategies of cancer immunotherapy, tumor immunogenic cell death …

Paclitaxel derivative-based liposomal nanoplatform for potentiated chemo-immunotherapy

Y Wang, J Yu, D Li, L Zhao, B Sun, J Wang… - Journal of Controlled …, 2022 - Elsevier
The combination of chemotherapy with the immune checkpoint blockade (ICB) therapy is
bringing a tremendous hope in the treatment of malignant tumors. However, the treatment …

[HTML][HTML] Diverse drug delivery systems for the enhancement of cancer immunotherapy: an overview

X Liu, Y Cheng, Y Liu, X Hu, T Wen - Frontiers in Immunology, 2024 - frontiersin.org
Despite the clear benefits demonstrated by immunotherapy, there is still an inevitable off-
target effect resulting in serious adverse immune reactions. In recent years, the research and …

Nanotechnology-mediated immunochemotherapy combined with docetaxel and PD-L1 antibody increase therapeutic effects and decrease systemic toxicity

Z Gu, Q Wang, Y Shi, Y Huang, J Zhang… - Journal of controlled …, 2018 - Elsevier
Immunotherapy has exhibited enormous practice in the treatment of melanoma because of
the intrinsic properties of tumor. Tumor can downmodulate immune function via multiple …

Immunogenic hybrid nanovesicles of liposomes and tumor-derived nanovesicles for cancer immunochemotherapy

M Hu, J Zhang, L Kong, Y Yu, Q Hu, T Yang, Y Wang… - Acs Nano, 2021 - ACS Publications
Exploring a rational delivery system of integrating chemotherapy with immunotherapy to
broaden benefits of cancer immunochemotherapy is still under challenge. Herein, we …

Engineering immunogenic cell death with nanosized drug delivery systems improving cancer immunotherapy

W Yan, T Lang, X Qi, Y Li - Current Opinion in Biotechnology, 2020 - Elsevier
Highlights•The immunogenic cell death (ICD) of cancer cells promotes immune
response.•Nanosized drug delivery systems can induce ICD.•Anti-cancer nanomedicines …

Stimuli‐responsive nanodelivery systems for amplifying immunogenic cell death in cancer immunotherapy

W Xu, W Liu, J Yang, J Lu, H Zhang… - Immunological …, 2024 - Wiley Online Library
Immunogenic cell death (ICD) is a special pattern of tumor cell death, enabling to elicit tumor‐
specific immune response via the release of damage‐associated molecular patterns and …

Liposomal delivery of mitoxantrone and a cholesteryl indoximod prodrug provides effective chemo-immunotherapy in multiple solid tumors

KC Mei, YP Liao, J Jiang, M Chiang, M Khazaieli… - ACS …, 2020 - ACS Publications
We developed a custom-designed liposome carrier for codelivery of a potent immunogenic
cell death (ICD) stimulus plus an inhibitor of the indoleamine 2, 3-dioxygenase (IDO-1) …

Enhancing TNBC Chemo-immunotherapy via combination reprogramming tumor immune microenvironment with Immunogenic Cell Death

S Wu, D Liu, W Li, B Song, C Chen, D Chen… - International Journal of …, 2021 - Elsevier
Tumor-associated fibroblasts (TAFs) play an important role in tumor progression and
therapeutic response, especially in the immunosuppressive tumor microenvironment (TME) …