Simple Summary Organoids, also known as self-organized 3D organ-like clusters, represent
almost a physiological system for studying cells, stem cells, tissues, and diseases, especially …

In vitro cell culture models are emerging as promising tools to understand human
development, disease progression, and provide reliable, rapid and cost-effective results for …

Colorectal cancer is the second leading cause of cancer death worldwide. Significant
advances in the molecular mechanisms underlying colorectal cancer have been made; …

Recent developments of organoids engineering and organ-on-a-chip microfluidic
technologies have enabled the recapitulation of the major functions and architectures of …

One of the problems that has slowed the development and approval of new anticancer
therapies is the lack of preclinical models that can be used to identify key molecular, cellular …

Microfluidic devices as translational research tools provide a potential alternative to animal
experiments due to their ability to mimic physiological parameters. Several approaches that …

The last few decades have witnessed diversified in vitro models to recapitulate the
architecture and function of living organs or tissues and contribute immensely to advances in …

Simple Summary Organ-on-a-chip models, or organ chips, are tiny devices designed to
accurately recreate the natural physiology and mechanical forces that cells experience in …

Every year, cancer causes millions of deaths around the globe, and researchers have been
engaged to provide novel therapies for this threatening disease. However, this process is …

Medicine today faces the combined challenge of an increasing number of untreatable
diseases and fewer drugs reaching the clinic. While pharmaceutical companies have …