Organoid cultures have emerged as powerful model systems accelerating discoveries in
cellular and cancer biology. These three-dimensional cultures are amenable to diverse …

In vitro cell cultures are crucial research tools for modeling human development and
diseases. Although the conventional monolayer cell cultures have been widely used in the …

Breast cancer has the highest cancer incidence rate in women worldwide. Therapies for
breast cancer have shown high success rates, yet many cases of recurrence and drug …

More than 90% of cancer-related deaths can be attributed to the occurrence of metastatic
diseases. Recent studies have highlighted the importance of the multicellular, biochemical …

“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …

Advances in organ-on-chip technologies for the application in in vitro drug development
provide an attractive alternative approach to replace ethically controversial animal testing …

Lab on a Chip and Integrative Biology journals. The issue includes a comprehensive
collection of research and review articles highlighting research and technology …

Developments in micro-and nanofluidic technologies have led to new kinds of cell culture
and screening systems that are collectively termed organ-on-a-chip systems. Organ-on-a …

New emerging technologies, remarkably miniaturized 3D organ models and microfluidics,
enable simulation of the real in vitro microenvironment ex vivo more closely. There are many …

Organ-on-a-chip (OOC) is a very ambitious emerging technology with a high potential to
revolutionize many medical and industrial sectors, particularly in preclinical-to-clinical …