[PDF][PDF] FOXP1 promotes embryonic neural stem cell differentiation by repressing Jagged1 expression
Mutations in FOXP1 have been linked to neurodevelopmental disorders including
intellectual disability and autism; however, the underlying molecular mechanisms remain ill …
intellectual disability and autism; however, the underlying molecular mechanisms remain ill …
[PDF][PDF] From pioneer to repressor: bimodal foxd3 activity dynamically remodels neural crest regulatory landscape in vivo
The neural crest (NC) is a transient embryonic stem cell-like population characterized by its
multipotency and broad developmental potential. Here, we perform NC-specific …
multipotency and broad developmental potential. Here, we perform NC-specific …
[HTML][HTML] Functional regulation of FoxO1 in neural stem cell differentiation
Forkhead transcription factor family O (FoxO) maintains adult stem cell reserves by
supporting their long-term proliferative potential. MicroRNAs (miRs) regulate neuronal …
supporting their long-term proliferative potential. MicroRNAs (miRs) regulate neuronal …
[HTML][HTML] Foxp1 Regulates Cortical Radial Migration and Neuronal Morphogenesis in Developing Cerebral Cortex
X Li, J Xiao, H Fröhlich, X Tu, L Li, Y Xu, H Cao, J Qu… - PloS one, 2015 - journals.plos.org
FOXP1 is a member of FOXP subfamily transcription factors. Mutations in FOXP1 gene have
been found in various development-related cognitive disorders. However, little is known …
been found in various development-related cognitive disorders. However, little is known …
Foxp1 in forebrain pyramidal neurons controls gene expression required for spatial learning and synaptic plasticity
DJ Araujo, K Toriumi, CO Escamilla… - Journal of …, 2017 - Soc Neuroscience
Genetic perturbations of the transcription factor Forkhead Box P1 (FOXP1) are causative for
severe forms of autism spectrum disorder that are often comorbid with intellectual disability …
severe forms of autism spectrum disorder that are often comorbid with intellectual disability …
[HTML][HTML] Dynamic and differential regulation of stem cell factor FoxD3 in the neural crest is Encrypted in the genome
MS Simoes-Costa, SJ McKeown, J Tan-Cabugao… - PLoS …, 2012 - journals.plos.org
The critical stem cell transcription factor FoxD3 is expressed by the premigratory and
migrating neural crest, an embryonic stem cell population that forms diverse derivatives …
migrating neural crest, an embryonic stem cell population that forms diverse derivatives …
[HTML][HTML] Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain
Forkhead-box protein P2 is a transcription factor that has been associated with intriguing
aspects of cognitive function in humans, non-human mammals, and song-learning birds …
aspects of cognitive function in humans, non-human mammals, and song-learning birds …
Foxp1 regulation of neonatal vocalizations via cortical development
The molecular mechanisms driving brain development at risk in autism spectrum disorders
(ASDs) remain mostly unknown. Previous studies have implicated the transcription factor …
(ASDs) remain mostly unknown. Previous studies have implicated the transcription factor …
Foxp2 regulates neuronal differentiation and neuronal subtype specification
YC Chiu, MY Li, YH Liu, JY Ding, JY Yu… - Developmental …, 2014 - Wiley Online Library
Mutations of the transcription factor FOXP2 in humans cause a severe speech and language
disorder. Disruption of Foxp2 in songbirds or mice also leads to deficits in song learning or …
disorder. Disruption of Foxp2 in songbirds or mice also leads to deficits in song learning or …
Identification and functional characterization of de novo FOXP1 variants provides novel insights into the etiology of neurodevelopmental disorder
E Sollis, SA Graham, A Vino, H Froehlich… - Human molecular …, 2016 - academic.oup.com
De novo disruptions of the neural transcription factor FOXP1 are a recently discovered, rare
cause of sporadic intellectual disability (ID). We report three new cases of FOXP1-related …
cause of sporadic intellectual disability (ID). We report three new cases of FOXP1-related …