Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers

D Kavvadias, G Scherer, F Cheung, G Errington… - Biomarkers, 2009 - Taylor & Francis
Tobacco-specific N-nitrosamines (TSNA) include 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK), N′-nitroso nornicotine (NNN), N′-nitroso anabasine (NAB) and N …

Tobacco-specific nitrosamines in the tobacco and mainstream smoke of US commercial cigarettes

SH Edwards, LM Rossiter, KM Taylor… - Chemical research in …, 2017 - ACS Publications
Tobacco-specific nitrosamines (TSNAs) are N-nitroso-derivatives of pyridine-alkaloids (eg,
nicotine) present in tobacco and cigarette smoke. Two TSNAs, N′-nitrosonornicotine (NNN) …

Investigation of exposure biomarkers in human plasma following differing levels of tobacco-specific N-nitrosamines and nicotine in cigarette smoke

J Zhang, X Liu, B Shi, Z Yang, Y Luo, T Xu, D Liu… - Environmental …, 2022 - Elsevier
Tobacco-specific N-nitrosamines (TSNAs) are strong carcinogens widely found in tobacco
products, environmental tobacco smoke, lake, and wastewater. The main objective of this …

Assessment of the exposure to tobacco-specific nitrosamines and minor tobacco alkaloids in users of various tobacco/nicotine products

G Scherer, M Scherer, J Mütze… - Chemical Research in …, 2022 - ACS Publications
Tobacco-specific nitrosamines (TSNAs), in particular, the human carcinogens 4-
(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N′-nitrosonornicotine (NNN), are …

[HTML][HTML] TSNA exposure from cigarette smoking: 18 years of urinary NNAL excretion data

S Appleton, RM Olegario, PJ Lipowicz - Regulatory toxicology and …, 2014 - Elsevier
The objective of this work was to characterize trends over time in urinary excretion of 4-
(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) among cigarette smokers in the US. We …

Proposed cutoff for identifying adult smokeless tobacco users with urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanonol: an aggregated analysis of NHANES …

IT Agaku, CI Vardavas… - Nicotine & tobacco …, 2013 - academic.oup.com
Abstract Introduction: NNAL [4-(methylnitrosamino)-1-(3-pyridyl)-1-butanonol] is a valid
biomarker of tobacco use. However; no study has assessed its use in distinguishing current …

Thirdhand exposures to tobacco-specific nitrosamines through inhalation, dust ingestion, dermal uptake, and epidermal chemistry

X Tang, N Benowitz, L Gundel, B Hang… - … science & technology, 2022 - ACS Publications
Tobacco-specific nitrosamines (TSNAs) are emitted during smoking and form indoors by
nitrosation of nicotine. Two of them, N′-nitrosonornicotine (NNN) and 4 …

Tobacco-specific nitrosamines in tobacco from US brand and non-US brand cigarettes

DL Ashley, MD Beeson, DR Johnson… - Nicotine & tobacco …, 2003 - academic.oup.com
Tobacco-specific nitrosamines (TSNAs) are one of the major classes of carcinogens found in
tobacco products. As part of collaborative efforts to reduce tobacco use and resulting …

Tobacco-specific nitrosamines in new tobacco products

I Stepanov, J Jensen, D Hatsukami… - Nicotine & Tobacco …, 2006 - academic.oup.com
New tobacco products, designed to attract consumers who are concerned about the health
effects of tobacco, have been appearing on the market. Objective evaluation of these …

Determination of carcinogenic tobacco-specific nitrosamines in mainstream smoke from US-brand and non-US-brand cigarettes from 14 countries

W Wu, L Zhang, RB Jain, DL Ashley… - Nicotine & tobacco …, 2005 - academic.oup.com
Tobacco-specific nitrosamines (TSNAs) comprise one of the major classes of carcinogenic
compounds in mainstream cigarette smoke. As part of collaborative efforts between the …