It is time to regulate carcinogenic tobacco-specific nitrosamines in cigarette tobacco

SS Hecht - Cancer Prevention Research, 2014 - AACR
Abstract The Family Smoking Prevention and Tobacco Control Act gives the US Food and
Drug Administration power to regulate tobacco products. This commentary calls for …

Presence of the Carcinogen N′-Nitrosonornicotine in Saliva of E-cigarette Users

G Bustamante, B Ma, G Yakovlev… - Chemical research in …, 2018 - ACS Publications
Many harmful constituents are present in e-cigarettes at much lower levels than in cigarette
smoke, and the results of analysis of urinary biomarkers in e-cigarette users are consistent …

[引用][C] Users of smokeless tobacco had higher levels of exposure to nicotine, carcinogens than cigarette smokers

C Printz - Cancer, 2016 - Wiley Online Library
Researchers from the Center for Tobacco Products at the US Food and Drug Administration
found that those who used smokeless tobacco exclusively had higher levels of exposure to …

Quantification of four tobacco-specific nitrosamines in cigarette filter tips using liquid chromatography-tandem mass spectrometry

PM Clayton, A Cunningham, JDH Van Heemst - Analytical methods, 2010 - pubs.rsc.org
Tobacco-specific N-nitrosamines (TSNA) have been suggested by some scientists to play an
important role in tobacco smoke carcinogenesis. We have developed and validated an LC …

Simultaneous determination of five tobacco-specific nitrosamines in mainstream cigarette smoke by isotope dilution liquid chromatography/electrospray ionization …

W Wu, DL Ashley, CH Watson - Analytical Chemistry, 2003 - ACS Publications
Tobacco-specific nitrosamines (TSNAs) have been previously implicated as a source of
carcinogenicity in tobacco and cigarette smoke. Accurate quantification of these chemicals is …

[PDF][PDF] Potentially reduced exposure tobacco products

V Rees, G Connolly, PA Patil, J Rothman… - Boston (MA): Harvard …, 2008 - researchgate.net
Introduction have variation in nicotine levels, including free nicotine, which potentially
influences consumption and tobacco dependence. Tobacco-specific nitrosamines can be …

50 Years of Research on Tobacco-Specific Nitrosamines: A Virtual Collection of Emerging Knowledge of Chemical Toxicology of Tobacco and Nicotine Delivery …

SS Hecht, PC Gupta, SJ Sturla… - Chemical research in …, 2022 - ACS Publications
Next year, Chemical Research in Toxicology will publish a virtual special issue to
commemorate the 50th anniversary of the first demonstration of the carcinogen N …

[HTML][HTML] Tobacco-specific N-nitrosamines NNN and NNK levels in cigarette brands between 2000 and 2014

I Gunduz, A Kondylis, G Jaccard, JM Renaud… - Regulatory Toxicology …, 2016 - Elsevier
The evolution of the levels of tobacco-specific N-nitrosamines (TSNA), N-nitrosonornicotine
(NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in mainstream (MS) …

A model to estimate the sources of tobacco-specific nitrosamines in cigarette smoke

PJ Lipowicz, JI Seeman - Chemical research in toxicology, 2017 - ACS Publications
Tobacco-specific nitrosamines (TSNAs) are one of the most extensively and continually
studied classes of compounds found in tobacco and cigarette smoke. 1− 5 The TSNAs N …

Tobacco‐specific N‐nitrosamines and polycyclic aromatic hydrocarbons in cigarettes smoked by the participants of the Shanghai Cohort Study

K Yershova, JM Yuan, R Wang… - … journal of cancer, 2016 - Wiley Online Library
Our recent studies on tobacco smoke carcinogen and toxicant biomarkers and cancer risk
among male smokers in the Shanghai Cohort Study showed that exposure to tobacco …