Gram-negative bacteria pose a serious public health concern, primarily due to a higher
frequency of antibiotic resistance conferred to them as a result of low permeability of their …

Gram-negative bacteria pose a serious public health concern due to resistance to many
antibiotics, caused by the low permeability of their outer membrane (OM). Effective …

The outer membrane (OM) in gram-negative bacteria contains proteins that regulate the
passive or active uptake of small molecules for growth and cell function, as well as mediate …

Antibiotic-resistant bacteria are becoming one of the most important problems in health care
because of the number of resistant strains and the paucity of new effective antimicrobials …

Variations in porin proteins are common in Gram-negative pathogens. Altered or absent
porins reduce access of polar antibiotics across the outer membrane and can thus contribute …

Mar (multiple antibiotic resistant) mutants of Escherichia coli express chromosomally
mediated resistance to a variety of structurally unrelated hydrophilic and hydrophobic …

Outer membrane protein F (OmpF) found in E. coli and related bacteria is post-
transcriptionally regulated by antisense micF RNA. During down regulation of ompF …

Gram-negative bacteria pose a significant public health concern since they are increasingly
becoming resistant to currently available antibiotics, and the development of new antibiotics …

Collective antibiotic drug resistance is a global threat, especially with respect to Gram-
negative bacteria. The low permeability of the bacterial outer cell wall has been identified as …

micF RNA, produced from a multicopy plasmid, was originally shown to be a major factor in
negative osmoregulation of the OmpF outer membrane protein in Escherichia coli. However …