In Escherichia coli, levels of the two major outer membrane porin proteins, OmpF and
OmpC, are regulated in response to a variety of environmental parameters, and numerous …

Publisher Summary There have been relatively rapid and dramatic changes in the antibiotic
resistance patterns in both community and institutional settings that will likely have …

Disruption of the outer membrane (OM) barrier allows for the entry of otherwise inactive
antimicrobials into Gram-negative pathogens. Numerous efforts to implement this approach …

Non‐coding small RNAs (sRNAs) play a major role in post‐transcriptional regulation of gene
expression. Of the 80 sRNAs that have been identified in E. coli, one‐third bind to the RNA …

Gram-negative bacteria cause the majority of highly drug-resistant bacterial infections. To
cross the outer membrane of the complex Gram-negative cell envelope, antibiotics permeate …

Bacteria have evolved several strategies to survive a myriad of harmful conditions in the
environment and in hosts. In Gram-negative bacteria, responses to nutrient limitation …

The OmpW family consists of a ubiquitous group of small outer membrane (OM) β-barrel
proteins of Gram-negative bacteria with proposed roles in environmental adaptation but …

Serratia marcescens is a Gram-negative enterobacterium that has become an important
opportunistic pathogen, largely due to its high degree of natural antibiotic resistance. One …

In Enterobacter aerogenes, multidrug resistance involves a decrease in outer membrane
permeability associated with changes in an as yet uncharacterized porin. We purified the …

Recent systematic genome searches revealed that bacteria encode a tremendous number
of small non-coding RNAs (sRNAs). Whereas most of these molecules remain of unknown …