Introduction Circadian rhythms are~ 24‐hour oscillations generated by a transcription‐
translation feedback loop known as the core molecular clock. The core clock is comprised of …

The intrinsic skeletal muscle core clock has emerged as a key feature of metabolic control
and influences several aspects of muscle physiology. Acute alcohol intoxication disrupts the …

Circadian rhythms are central to optimal physiological function, as disruption contributes to
the development of several chronic diseases. Alcohol (EtOH) intoxication disrupts circadian …

Circadian rhythms are central to optimal physiological function as disruption contributes to
the 43 development of several chronic diseases. Alcohol (EtOH) intoxication disrupts …

The skeletal muscle clock contributes to the regulation of skeletal muscle health and
function. Mutations to the muscle clock result in decreased muscle mass and strength …

Circadian rhythms and metabolic homeostasis are closely entangled biological processes.
Clock genes refer to a group of genes which regulate a variety of biological responses …

Background Skeletal muscle is a major contributor to whole-body metabolism as it serves as
a depot for both glucose and amino acids, and is a highly metabolically active tissue. Within …

Circadian rhythms regulate a host of physiological processes in a time-dependent manner to
maintain homeostasis in response to various environmental stimuli like day and night cycles …

Emerging evidence from both experimental animal studies and clinical human investigations
demonstrates strong connections among circadian processes, alcohol use, and alcohol …

The circadian rhythm, with the form of a transcription-translation negative feedback loop, is
present in skeletal muscle tissue and is regulated by several core clock genes. In addition …