Opa proteins of pathogenic neisseriae initiate Src kinase-dependent or lipid raft-mediated uptake via distinct human carcinoembryonic antigen-related cell adhesion …

T Schmitter, S Pils, S Weibel, F Agerer… - Infection and …, 2007 - Am Soc Microbiol
Several pathogenic bacteria exploit human carcinoembryonic antigen-related cell adhesion
molecules (CEACAMs) for adhesion to and invasion into their host cells. CEACAM isoforms …

[HTML][HTML] Distinct mechanisms of internalization of Neisseria gonorrhoeae by members of the CEACAM receptor family involving Rac1‐and Cdc42‐dependent and …

O Billker, A Popp, V Brinkmann, G Wenig… - The EMBO …, 2002 - embopress.org
Opa adhesins of pathogenic Neisseria species target four members of the human
carcinoembryonic antigen‐related cellular adhesion molecule (CEACAM) family. CEACAM …

Global Analysis of Neutrophil Responses to Neisseria gonorrhoeae Reveals a Self-Propagating Inflammatory Program

A Sintsova, H Sarantis, EA Islam, CX Sun… - PLoS …, 2014 - journals.plos.org
An overwhelming neutrophil-driven response causes both acute symptoms and the lasting
sequelae that result from infection with Neisseria gonorrhoeae. Neutrophils undergo an …

Uropathogenic E. coli Exploit CEA to Promote Colonization of the Urogenital Tract Mucosa

P Muenzner, A Kengmo Tchoupa, B Klauser… - PLoS …, 2016 - journals.plos.org
Attachment to the host mucosa is a key step in bacterial pathogenesis. On the apical surface
of epithelial cells, members of the human carcinoembryonic antigen (CEA) family are …

Engulfment of Neisseria gonorrhoeae: Revealing Distinct Processes of Bacterial Entry by Individual Carcinoembryonic Antigen-Related Cellular Adhesion Molecule …

SE McCaw, EH Liao, SD Gray-Owen - Infection and immunity, 2004 - Am Soc Microbiol
Individual Neisseria gonorrhoeae colony opacity-associated (Opa) protein variants can bind
up to four different carcinoembryonic antigen-related cellular adhesion molecule (CEACAM) …

Pathogenic Neisseria trigger expression of their carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1; previously CD66a) receptor on primary …

P Muenzner, M Naumann, TF Meyer… - Journal of Biological …, 2001 - ASBMB
Neisseria gonorrhoeae express opacity-associated (Opa) protein adhesins that mediate
binding to various members of the carcinoembryonic antigen-related cellular adhesion …

Differential recognition of members of the carcinoembryonic antigen family by Opa variants of Neisseria gonorrhoeae

MP Bos, F Grunert, RJ Belland - Infection and immunity, 1997 - Am Soc Microbiol
Opacity (Opa) protein variation in Neisseria gonorrhoeae is implicated in the pathogenesis
of gonorrhea, possibly by mediating adherence and entry of the bacteria into human tissues …

Opa proteins and CEACAMs: pathways of immune engagement for pathogenic Neisseria

M Sadarangani, AJ Pollard… - FEMS microbiology …, 2011 - academic.oup.com
Neisseria meningitidis and Neisseria gonorrhoeae are globally important pathogens, which
in part owe their success to their ability to successfully evade human immune responses …

Neisseria gonorrhoeae Kills Carcinoembryonic Antigen-Related Cellular Adhesion Molecule 1 (CD66a)-Expressing Human B Cells and Inhibits Antibody Production

M Pantelic, YJ Kim, S Bolland, I Chen… - Infection and …, 2005 - Am Soc Microbiol
Neisseria gonorrhoeae cells (gonococci [GC]), the etiological agents for gonorrhea, can
cause repeated infections. During and after gonococcal infection, local and systemic …

Variable expression of opa proteins by Neisseria gonorrhoeae influences bacterial association and phagocytic killing by human neutrophils

AM Alcott, LM Werner, CM Baiocco… - Journal of …, 2022 - Am Soc Microbiol
Neisseria gonorrhoeae infection is characterized by local and abundant recruitment of
neutrophils. Despite neutrophils' antimicrobial activities, viable N. gonorrhoeae is recovered …