Carcino-embryonic antigen-like cellular adhesion molecules (CEACAMs), members of the
immunoglobulin superfamily, are responsible for cell–cell interactions and cellular signaling …

Background Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), an
immunoglobulin (Ig)-related glycoprotein, serves as cellular receptor for a variety of Gram …

Neisserial Opa proteins function as a family of adhesins that bind heparan sulfate
proteoglycan (HSPG) or carcinoembryonic antigen family (CEACAM) receptors on human …

Neisseria gonorrhoeae is the causative microorganism for the sexually transmitted disease
(STD) gonorrhea and humans are its only natural host. An animal model would be a useful …

Gonorrhea is characterized by a purulent urethral or cervical discharge consisting primarily
of neutrophils associated with Neisseria gonorrhoeae. These interactions are facilitated by …

Neisseria gonorrhoeae can be internalized by mammalian cells through interactions
between bacterial Opa adhesins and members of the human carcinoembryonic antigen …

Sexually transmitted infections are a critical public health issue. However, the mechanisms
underlying sexually transmitted infections in women and the link between the infection …

Fig. 1. This receptor domain is characterized by the absence of glycosylation and–in other
members of the immunoglobulin superfamily–is involved in protein–protein interactions with …

Neisseria gonorrhoeae (gonococci, GC) are phagocytosed by neutrophils through the
interaction between opacity proteins (Opa) and the CEA (CD66) family of antigens. In order …

Background Human CEACAM1 is a cell-cell adhesion molecule with multiple functions
including insulin clearance in the liver, vasculogenesis in endothelial cells, lumen formation …