[图书][B] Genetic adaptation contributing to increased gonococcal fitness during vaginal infection of CEACAM-humanized mice
J Lam - 2017 - search.proquest.com
Neisseria gonorrhoeae (Gc), the obligate human pathogen responsible for gonorrhea, has
drastic consequences on reproductive health, if left untreated. Although, vaginal infection in …
drastic consequences on reproductive health, if left untreated. Although, vaginal infection in …
Several carcinoembryonic antigens (CD66) serve as receptors for gonococcal opacity proteins
T Chen, F Grunert, A Medina-Marino… - The Journal of …, 1997 - rupress.org
Neisseria gonorrhoeae (GC) is a human pathogen that adheres to and invades genital
surfaces. Although pili are required for the initial adherence, the interaction of GC with …
surfaces. Although pili are required for the initial adherence, the interaction of GC with …
Expression of pathogen‐like Opa adhesins in commensal Neisseria: genetic and functional analysis
M Toleman, E Aho, M Virji - Cellular microbiology, 2001 - Wiley Online Library
Several species of commensal Neisseriae (Cn) may colonize the human nasopharynx, but
little is known about their adhesion mechanisms. We have investigated structural and …
little is known about their adhesion mechanisms. We have investigated structural and …
[HTML][HTML] Extracellular IgC2 Constant Domains of CEACAMs Mediate PI3K Sensitivity during Uptake of Pathogens
M Voges, V Bachmann, J Naujoks, K Kopp, CR Hauck - PloS one, 2012 - journals.plos.org
Background Several pathogenic bacteria utilize receptors of the CEACAM family to attach to
human cells. Binding to different members of this receptor family can result in uptake of the …
human cells. Binding to different members of this receptor family can result in uptake of the …
In Vivo Selection for Neisseria gonorrhoeae Opacity Protein Expression in the Absence of Human Carcinoembryonic Antigen Cell Adhesion Molecules
AN Simms, AE Jerse - Infection and immunity, 2006 - Am Soc Microbiol
The neisserial opacity (Opa) proteins are phase-variable, antigenically distinct outer
membrane proteins that mediate adherence to and invasion of human cells. We previously …
membrane proteins that mediate adherence to and invasion of human cells. We previously …
[HTML][HTML] Association of Neisseria gonorrhoeae OpaCEA with Dendritic Cells Suppresses Their Ability to Elicit an HIV-1-Specific T Cell Memory Response
Q Yu, EMC Chow, SE McCaw, N Hu, D Byrd, T Amet… - PloS one, 2013 - journals.plos.org
Infection with Neisseria gonorrhoeae (N. gonorrhoeae) can trigger an intense local
inflammatory response at the site of infection, yet there is little specific immune response or …
inflammatory response at the site of infection, yet there is little specific immune response or …
Neisseria gonorrhoeae evades host immunity by switching off T lymphocytes
J Bradbury - The Lancet, 2002 - thelancet.com
New research on Neisseria gon-orrhoeae may help to explain the success of this human
pathogen.“We have discovered that when gonococcal Opa proteins bind to a receptor on …
pathogen.“We have discovered that when gonococcal Opa proteins bind to a receptor on …
[HTML][HTML] The CGM1a (CEACAM3/CD66d)-mediated phagocytic pathway of Neisseria gonorrhoeae expressing opacity proteins is also the pathway to cell death
T Chen, S Bolland, I Chen, J Parker, M Pantelic… - Journal of Biological …, 2001 - ASBMB
Phagocytosis of Opa+ Neisseria gonorrhoeae (gonococcus, GC) by neutrophils is in part
dependent on the interaction of Opa proteins with CGM1a (CEACAM3/CD66d) antigens, a …
dependent on the interaction of Opa proteins with CGM1a (CEACAM3/CD66d) antigens, a …
The N‐domain of the human CD66a adhesion molecule is a target for Opa proteins of Neisseria meningitidis and Neisseria gonorrhoeae
M Virji, SM Watt, S Barker, K Makepeace… - Molecular …, 1996 - Wiley Online Library
Using COS (African green monkey kidney) cells transfected with cDNAs encoding human
cell surface molecules, we have identified human cellular receptors for meningococcal …
cell surface molecules, we have identified human cellular receptors for meningococcal …
[HTML][HTML] Neisseria meningitidis Has Two Independent Modes of Recognizing Its Human Receptor CEACAM1
K Kuespert, A Roth, CR Hauck - PloS one, 2011 - journals.plos.org
Background Several human-restricted Gram-negative bacteria exploit carcinoembryonic
antigen-related cell adhesion molecules (CEACAMs) for host colonization. For example …
antigen-related cell adhesion molecules (CEACAMs) for host colonization. For example …