The neisserial opacity (Opa) proteins are a family of antigenically distinct outer membrane
proteins that undergo phase-variable expression. Opa+ variants of Neisseria gonorrhoeae …

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) are used by several
human pathogens to anchor themselves to or invade host cells. Interestingly, human …

It is now well established that the major receptors targeted by neisserial Opa proteins belong
to the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family of …

The neutrophil‐specific innate immune receptor CEACAM3 functions as a decoy to capture
Gram‐negative pathogens, such as Neisseria gonorrhoeae, that exploit CEACAM family …

The pathological features of ascending gonococcal infection suggest that proinflammatory
mediators secreted by tissue-resident macrophages are important components of the host …

The Neisseria gonorrhoeae (the gonococcus [Gc]) opacity-associated (Opa) proteins
mediate bacterial binding and internalization by human epithelial cells and neutrophils …

Life-threatening bacterial infections in women after childbirth, known as puerperal sepsis,
resulted in classical epidemics and remain a global health problem. While outbreaks of …

Neisseria gonorrhoeae induces local infections in the human genitourinary tract and can
disseminate to other organs to cause severe disease. Blood-derived factors present in the …

Neisseria gonorrhoeae (GC) or Escherichia coli expressing phase-variable opacity (Opa)
protein (Opa+ GC or Opa+ E. coli) adhere to human neutrophils and stimulate phagocytosis …

Several Gram-negative human pathogens recognize members of the carcinoembryonic
antigen-related cell adhesion molecule (CEACAM) family. Pathogenic Neisseriae employ …