Differential response of human monocytes to Neisseria gonorrhoeae variants expressing pili and opacity proteins

B Knepper, I Heuer, TF Meyer… - Infection and …, 1997 - Am Soc Microbiol
Experiments in vitro suggest that Neisseria gonorrhoeae surface variation plays a key role in
gonococcal pathogenesis by providing the appropriate bacterial phenotypes to go through …

Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site

SM Watt, AM Teixeira, GQ Zhou… - Blood, The Journal …, 2001 - ashpublications.org
CEACAM1 on leukocytic, endothelial, and epithelial cells functions in homophilic adhesion,
tumor suppression, regulating cell adhesion and proliferation, and in heterophilic adhesion …

Mutational analysis of human CEACAM1: the potential of receptor polymorphism in increasing host susceptibility to bacterial infection

S Villullas, DJ Hill, RB Sessions, J Rea… - Cellular …, 2007 - Wiley Online Library
A common overlapping site on the N‐terminal IgV‐like domain of human carcinoembryonic
antigen (CEA)‐related cell adhesion molecules (CEACAMs) is targeted by several important …

Neisseria gonorrhoeae infects the human endocervix by activating non-muscle myosin II-mediated epithelial exfoliation

LC Wang, Q Yu, V Edwards, B Lin, J Qiu… - PLoS …, 2017 - journals.plos.org
Colonization and disruption of the epithelium is a major infection mechanism of mucosal
pathogens. The epithelium counteracts infection by exfoliating damaged cells while …

The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled‐coil

R Conners, DJ Hill, E Borodina, C Agnew… - The EMBO …, 2008 - embopress.org
Moraxella catarrhalis is a ubiquitous human‐specific bacterium commonly associated with
upper and lower respiratory tract infections, including otitis media, sinusitis and chronic …

Signaling by epithelial members of the CEACAM family–mucosal docking sites for pathogenic bacteria

AK Tchoupa, T Schuhmacher, CR Hauck - Cell communication and …, 2014 - Springer
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) comprise a group
of immunoglobulin-related vertebrate glycoproteins. Several family members, including …

Homologue scanning mutagenesis reveals CD66 receptor residues required for neisserial Opa protein binding

MP Bos, D Hogan, RJ Belland - The Journal of experimental medicine, 1999 - rupress.org
The immunoglobulin-like family of CD66 antigens, present on human neutrophils and
epithelial cells, are used as receptors for adhesins expressed by the pathogenic Neisseriae …

Adhesion molecules associated with female genital tract infection

J Qualai, J Cantero, LX Li, JM Carrascosa, E Cabre… - Plos one, 2016 - journals.plos.org
Efforts to develop vaccines that can elicit mucosal immune responses in the female genital
tract against sexually transmitted infections have been hampered by an inability to measure …

Pivotal role of CEACAM1 protein in the inhibition of activated decidual lymphocyte functions

G Markel, D Wolf, J Hanna, R Gazit… - The Journal of …, 2002 - Am Soc Clin Investig
Lymphocytes in direct contact with embryonic extravillous trophoblasts constitute more than
40% of decidual cells and appear to play major roles in implantation and early gestation. A …

Expression of human CEACAM1 in transgenic mice limits the Opa-specific immune response against meningococcal outer membrane vesicles

A Zariri, H van Dijken, HJ Hamstra, M van der Flier… - Vaccine, 2013 - Elsevier
Outer membrane vesicles (OMVs) have been extensively investigated as meningococcal
vaccine candidates. Among their major components are the opacity (Opa) proteins, a family …