Genetics of resilience: Implications from genome‐wide association studies and candidate genes of the stress response system in posttraumatic stress disorder and …

S Maul, I Giegling, C Fabbri, F Corponi… - American Journal of …, 2020 - Wiley Online Library
Resilience is the ability to cope with critical situations through the use of personal and
socially mediated resources. Since a lack of resilience increases the risk of developing …

Genomics and psychological resilience: a research agenda

KW Choi, MB Stein, EC Dunn, KC Koenen… - Molecular …, 2019 - nature.com
Although exposure to adversity increases risk for poor mental health outcomes, many
people exposed to adversity do not develop such outcomes. Psychological resilience …

Genome‐wide analyses of psychological resilience in US Army soldiers

MB Stein, KW Choi, S Jain… - American Journal of …, 2019 - Wiley Online Library
Though a growing body of preclinical and translational research is illuminating a biological
basis for resilience to stress, little is known about the genetic basis of psychological …

Risk and resilience: genetic and environmental influences on development of the stress response

CF Gillespie, J Phifer, B Bradley… - Depression and …, 2009 - Wiley Online Library
Exposure to stressful events during development has consistently been shown to produce
long‐lasting alterations in the hypothalamic‐pituitary‐adrenal (HPA) axis, which may …

The relationship between genetic and environmental influences on resilience and on common internalizing and externalizing psychiatric disorders

AB Amstadter, HH Maes, CM Sheerin, JM Myers… - Social psychiatry and …, 2016 - Springer
Purpose Resilience to stressful life events (SLEs), which increase risk of psychopathology, is
influenced by genetic factors. The purpose of this paper was to map the overlap of etiologic …

[HTML][HTML] The genetics of stress-related disorders: PTSD, depression, and anxiety disorders

JW Smoller - Neuropsychopharmacology, 2016 - nature.com
Research into the causes of psychopathology has largely focused on two broad etiologic
factors: genetic vulnerability and environmental stressors. An important role for …

[HTML][HTML] The molecular basis of resilience: a narrative review

M Ryan, R Ryznar - Frontiers in Psychiatry, 2022 - frontiersin.org
Resilience refers to the adaptability of a person–an ability to “bounce-back” from stressors.
We question if resilience can be strengthened, potentially to decrease the risk of stress …

Epigenetics of posttraumatic stress disorder: current evidence, challenges, and future directions

AS Zannas, N Provençal, EB Binder - Biological psychiatry, 2015 - Elsevier
Posttraumatic stress disorder (PTSD) is a stress-related psychiatric disorder that is thought to
emerge from complex interactions among traumatic events and multiple genetic factors …

Genomic prediction of depression risk and resilience under stress

Y Fang, L Scott, P Song, M Burmeister… - Nature human …, 2020 - nature.com
Advancing ability to predict who is likely to develop depression holds great potential in
reducing the disease burden. Here, we use the predictable and large increase in depression …

Genetic variation in 5HTTLPR is associated with emotional resilience

MB Stein, L Campbell‐Sills… - American Journal of …, 2009 - Wiley Online Library
Emotional resilience can be defined as the ability to maintain healthy and stable levels of
psychological functioning in the wake of stress and trauma. Although genes that contribute …