The metabolic landscape of breast cancer and its therapeutic implications

Z Jiao, Y Pan, F Chen - Molecular Diagnosis & Therapy, 2023 - Springer
Breast cancer is the most common malignant tumor globally as of 2020 and remains the
second leading cause of cancer-related death among female individuals worldwide …

Perspectives of reprogramming breast cancer metabolism

YP Wang, QY Lei - Translational Research in Breast Cancer: Biomarker …, 2017 - Springer
Reprogramming of cellular metabolism is one of the hallmarks of breast cancer. Breast
cancer cells remodel metabolic network to maintain their transformed state and survive in a …

Metabolic reprogramming in breast cancer

C Scatena, AG Naccarato, B Ozsvari… - Frontiers in …, 2022 - frontiersin.org
Metabolic reprogramming is an emerging hallmark of breast cancer. A common
characteristic of tumor cells is the ability to obtain nutrients from a nutrient-deprived …

[HTML][HTML] Energy metabolism pathways in breast cancer progression: The reprogramming, crosstalk, and potential therapeutic targets

X Zheng, H Ma, J Wang, M Huang, D Fu, L Qin… - Translational …, 2022 - Elsevier
Breast cancer (BC) is a malignant tumor that seriously endangers health in women. BC, like
other cancers, is accompanied by metabolic reprogramming. Among energy metabolism …

Metabolic flexibility is a determinant of breast cancer heterogeneity and progression

M Fukano, M Park, G Deblois - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer comprises a wide variety of cancer cells that present distinct
phenotypes and develop various nutrient dependencies to grow and survive in stressful …

Uncovering the metabolomic fingerprint of breast cancer

C Oakman, L Tenori, L Biganzoli, L Santarpia… - The international journal …, 2011 - Elsevier
Metabolomics, the study of metabolites and small intermediate molecules, may play a key
role in further elucidation of breast cancer. This dynamic, simultaneous assessment of …

Metabolic reprogramming in breast cancer and its therapeutic implications

N Gandhi, GM Das - Cells, 2019 - mdpi.com
Current standard-of-care (SOC) therapy for breast cancer includes targeted therapies such
as endocrine therapy for estrogen receptor-alpha (ERα) positive; anti-HER2 monoclonal …

Deciphering metabolic rewiring in breast cancer subtypes

MP Ogrodzinski, JJ Bernard, SY Lunt - Translational Research, 2017 - Elsevier
Metabolic reprogramming, an emerging hallmark of cancer, is observed in breast cancer.
Breast cancer cells rewire their cellular metabolism to meet the demands of survival …

Metabolic implication of tumor: stroma crosstalk in breast cancer

A Morandi, P Chiarugi - Journal of molecular medicine, 2014 - Springer
The metabolic properties of cancer cells significantly differ from those of normal cells. In
particular, cancer cells are largely dependent on aerobic glycolysis, a phenomenon that has …

[HTML][HTML] On metabolic reprogramming and tumor biology: A comprehensive survey of metabolism in breast cancer

J Penkert, T Ripperger, M Schieck, B Schlegelberger… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Altered metabolism in tumor cells has been a focus of cancer research for as long as a
century but has remained controversial and vague due to an inhomogeneous overall …