Polyadenylation at the 3′ ends of mRNAs is critical to the translation and stability of the
messages. Recently determined structures of poly (A) polymerase, U1A and domains of the …

Most eukaryotic mRNAs and different non‐coding RNAs undergo a form of 3′ end
processing known as polyadenylation. Polyadenylation machinery is present in almost all …

There has been rapid progress over the past 3-4 years in elucidating the functions of the
poly (A) tail in both eukaryotes and prokaryotes. As a large number of previous experiments …

Posttranscriptional maturation of the 3′ end of eukaryotic pre-mRNAs occurs as a three-
step pathway involving site-specific cleavage, polymerization of a poly (A) tail, and trimming …

Poly (A) tails of mRNAs are synthesized in the cell nucleus with a defined length,∼ 250
nucleotides in mammalian cells. The same type of length control is seen in an in vitro …

Polyadenylation is the non-template addition of adenosine nucleotides at the 3'-end of RNA,
which occurs after transcription and generates a poly (A) tail up to 250–300 nucleotides …

During their synthesis in the cell nucleus, most eukaryotic mRNAs undergo a two‐step 3′‐
end processing reaction in which the pre‐mRNA is cleaved and released from the …

The status of the poly (A) tail at the 3′-end of mRNAs controls the expression of numerous
genes in response to developmental and extracellular signals. Poly (A) tail regulation …

A poly (A) tail is found at the 3 end of nearly every fully processed eukaryotic mRNA and has
been suggested to influence virtually all aspects of mRNA metabolism. Its proposed …

Poly (A) tails are commonly found at the 3'end of various classes of RNA (reviewed in
Brawerman 1981; Manley 1995b). They are evolutionarily widespread and appear on RNAs …