Invasive fungal infections pose a major threat to human health. Bacterial and protozoan
pathogens secrete protein effectors that overcome innate immune barriers to promote …

Medically important fungi range from commensal organisms that cause opportunistic
infections to primary fungal pathogens that can cause disease in immunocompetent hosts …

The incidence of life-threatening fungal infections has continued to increase in recent years,
predominantly in patients debilitated by iatrogenic interventions or immunological …

Fungal diseases contribute significantly to morbidity and mortality in humans. Although
recent research has improved our understanding of the complex and dynamic interplay that …

The human immune system uses an arsenal of effector mechanisms to prevent and
counteract infections. Yet, some fungal species are extremely successful as human …

Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

Innate immunity is an ancient cell-autonomous property of eukaryotes that allows them to
regulate interactions with antagonistic microbes, including bacteria. While animal and plant …

Fungi are eukaryotic heterotrophs present in virtually every environment, with potentially
more than 5 million individual species (1). Despite this impressive biodiversity, only about …

Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …

Editorial summary Understanding the complex and highly dynamic interactions between
fungi and host cells in a tissue-specific manner is crucial to facilitate the development of new …